TFPI2-DT

Summary

TFPI2-DT (TFPI2 divergent transcript, HGNC:40581) is a long non-coding RNA gene on chromosome 7q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40581
Approved symbol	TFPI2-DT
Name	TFPI2 divergent transcript
Location	7q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000234695
Ensembl biotype	lncRNA
Entrez	105375401
RNAcentral	URS0000A76C9B — lncRNA, 533 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000435257

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435257 — 2 exons

Exon	Start	End
ENSE00004226447	93893242	93893993
ENSE00004226448	93890824	93891079

Expression profiles

Bgee: expression breadth ubiquitous, 105 present calls, max score 81.02.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0524 / max 27.5875, expressed in 13 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
79571	0.0297	7
79570	0.0197	4
204525	0.0030	1

Top tissues by expression

105 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.02	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.07	gold quality
placenta	UBERON:0001987	62.49	gold quality
islet of Langerhans	UBERON:0000006	60.76	gold quality
muscle tissue	UBERON:0002385	59.34	gold quality
endometrium	UBERON:0001295	58.97	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	57.54	gold quality
skeletal muscle tissue	UBERON:0001134	57.23	silver quality
pancreas	UBERON:0001264	57.04	gold quality
gall bladder	UBERON:0002110	55.35	gold quality
monocyte	CL:0000576	54.70	gold quality
body of pancreas	UBERON:0001150	54.61	gold quality
liver	UBERON:0002107	53.76	gold quality
blood	UBERON:0000178	53.62	gold quality
right adrenal gland cortex	UBERON:0035827	53.24	gold quality
smooth muscle tissue	UBERON:0001135	51.31	gold quality
right adrenal gland	UBERON:0001233	51.22	gold quality
prefrontal cortex	UBERON:0000451	50.93	gold quality
left adrenal gland cortex	UBERON:0035825	50.93	gold quality
kidney	UBERON:0002113	50.73	gold quality
urinary bladder	UBERON:0001255	50.42	gold quality
adrenal gland	UBERON:0002369	50.28	gold quality
ovary	UBERON:0000992	50.27	gold quality
left ovary	UBERON:0002119	50.14	gold quality
adult mammalian kidney	UBERON:0000082	49.96	gold quality
muscle of leg	UBERON:0001383	49.85	gold quality
left adrenal gland	UBERON:0001234	49.75	gold quality
cortex of kidney	UBERON:0001225	49.44	gold quality
adrenal tissue	UBERON:0018303	48.99	silver quality
primary visual cortex	UBERON:0002436	48.53	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.