TGFA-IT1

Summary

TGFA-IT1 (TGFA intronic transcript 1, HGNC:41389) is a long non-coding RNA gene on chromosome 2p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41389
Approved symbol	TGFA-IT1
Name	TGFA intronic transcript 1
Location	2p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224606
Ensembl biotype	lncRNA
Entrez	100874273
RNAcentral	URS000075BE03 — lncRNA, 492 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000441238

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000441238 — 2 exons

Exon	Start	End
ENSE00001692214	70468372	70468495
ENSE00001725062	70467385	70467696

Expression profiles

Bgee: expression breadth broad, 58 present calls, max score 62.21.

Top tissues by expression

58 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
tonsil	UBERON:0002372	62.21	silver quality
endometrium	UBERON:0001295	57.39	gold quality
blood	UBERON:0000178	57.02	gold quality
monocyte	CL:0000576	56.72	gold quality
uterine cervix	UBERON:0000002	56.63	gold quality
primary visual cortex	UBERON:0002436	55.10	gold quality
anterior cingulate cortex	UBERON:0009835	53.49	gold quality
prefrontal cortex	UBERON:0000451	52.66	gold quality
islet of Langerhans	UBERON:0000006	52.34	gold quality
corpus callosum	UBERON:0002336	50.24	gold quality
left ovary	UBERON:0002119	48.61	gold quality
body of pancreas	UBERON:0001150	47.99	gold quality
adrenal gland	UBERON:0002369	47.51	silver quality
substantia nigra	UBERON:0002038	47.19	gold quality
tibial artery	UBERON:0007610	46.72	gold quality
heart	UBERON:0000948	46.65	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	46.38	gold quality
esophagus	UBERON:0001043	46.21	gold quality
esophagus mucosa	UBERON:0002469	45.81	gold quality
stomach	UBERON:0000945	45.74	gold quality
vagina	UBERON:0000996	45.74	gold quality
multicellular organism	UBERON:0000468	45.59	gold quality
lower esophagus mucosa	UBERON:0035834	45.51	silver quality
body of stomach	UBERON:0001161	45.39	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	44.88	silver quality
adult mammalian kidney	UBERON:0000082	44.70	silver quality
muscle layer of sigmoid colon	UBERON:0035805	44.28	silver quality
left adrenal gland	UBERON:0001234	44.20	gold quality
heart left ventricle	UBERON:0002084	43.84	silver quality
colon	UBERON:0001155	43.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.98

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.