TGFB3-AS1

Summary

TGFB3-AS1 (TGFB3 antisense RNA 1, HGNC:53144) is a long non-coding RNA gene on chromosome 14q24.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53144
Approved symbol	TGFB3-AS1
Name	TGFB3 antisense RNA 1
Location	14q24.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000553732
Ensembl gene	ENSG00000258876
Ensembl biotype	lncRNA
Entrez	109729179
RNAcentral	URS000044164A — lncRNA, 580 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000553732

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553732 — 2 exons

Exon	Start	End
ENSE00002491689	75970924	75971331
ENSE00002513887	75971416	75971587

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 67.76.

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	67.76	gold quality
sural nerve	UBERON:0015488	65.30	silver quality
ganglionic eminence	UBERON:0004023	64.59	gold quality
skeletal muscle tissue	UBERON:0001134	64.09	gold quality
endocervix	UBERON:0000458	61.08	gold quality
placenta	UBERON:0001987	60.22	gold quality
body of pancreas	UBERON:0001150	60.21	gold quality
lymph node	UBERON:0000029	60.03	gold quality
popliteal artery	UBERON:0002250	59.84	gold quality
tibial artery	UBERON:0007610	59.82	gold quality
smooth muscle tissue	UBERON:0001135	59.70	gold quality
body of uterus	UBERON:0009853	59.54	gold quality
ascending aorta	UBERON:0001496	59.42	gold quality
pancreas	UBERON:0001264	59.14	gold quality
left coronary artery	UBERON:0001626	58.85	gold quality
thoracic aorta	UBERON:0001515	58.80	gold quality
prostate gland	UBERON:0002367	58.74	gold quality
hindlimb stylopod muscle	UBERON:0004252	58.69	gold quality
urinary bladder	UBERON:0001255	58.36	gold quality
superior frontal gyrus	UBERON:0002661	58.27	gold quality
liver	UBERON:0002107	58.08	gold quality
myometrium	UBERON:0001296	58.01	gold quality
omental fat pad	UBERON:0010414	57.66	gold quality
descending thoracic aorta	UBERON:0002345	56.93	gold quality
gall bladder	UBERON:0002110	56.67	gold quality
muscle of leg	UBERON:0001383	56.58	gold quality
mucosa of stomach	UBERON:0001199	56.26	gold quality
gastrocnemius	UBERON:0001388	56.25	gold quality
adipose tissue	UBERON:0001013	56.07	gold quality
right lobe of liver	UBERON:0001114	55.71	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.31

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.