TGFBRAP1-AS1

Summary

TGFBRAP1-AS1 (TGFBRAP1 antisense RNA 1, HGNC:56908) is a long non-coding RNA gene on chromosome 2q12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56908
Approved symbol	TGFBRAP1-AS1
Name	TGFBRAP1 antisense RNA 1
Location	2q12.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC012360.1
Ensembl gene	ENSG00000235319
Ensembl biotype	lncRNA
Entrez	132503825
RNAcentral	URS00001C532D — lncRNA, 674 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000433219

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433219 — 4 exons

Exon	Start	End
ENSE00001640350	105327237	105327301
ENSE00001710825	105330098	105330529
ENSE00001739396	105324210	105324285
ENSE00001760305	105325022	105325122

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 90.64.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	90.64	gold quality
ventricular zone	UBERON:0003053	63.90	gold quality
bone marrow cell	CL:0002092	63.40	silver quality
ganglionic eminence	UBERON:0004023	62.84	gold quality
bone marrow	UBERON:0002371	56.79	gold quality
monocyte	CL:0000576	56.07	gold quality
islet of Langerhans	UBERON:0000006	55.18	gold quality
prefrontal cortex	UBERON:0000451	55.09	gold quality
tonsil	UBERON:0002372	54.00	gold quality
calcaneal tendon	UBERON:0003701	53.47	silver quality
nucleus accumbens	UBERON:0001882	52.79	gold quality
mucosa of transverse colon	UBERON:0004991	51.97	gold quality
stromal cell of endometrium	CL:0002255	51.76	silver quality
putamen	UBERON:0001874	51.64	gold quality
duodenum	UBERON:0002114	51.63	gold quality
gall bladder	UBERON:0002110	51.25	gold quality
muscle of leg	UBERON:0001383	50.95	gold quality
lymph node	UBERON:0000029	50.86	gold quality
blood	UBERON:0000178	50.86	gold quality
right lobe of liver	UBERON:0001114	50.51	gold quality
gastrocnemius	UBERON:0001388	50.47	gold quality
frontal cortex	UBERON:0001870	50.42	gold quality
vermiform appendix	UBERON:0001154	50.32	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.26	gold quality
liver	UBERON:0002107	50.00	gold quality
placenta	UBERON:0001987	49.69	gold quality
primary visual cortex	UBERON:0002436	49.30	gold quality
Brodmann (1909) area 9	UBERON:0013540	49.25	gold quality
brain	UBERON:0000955	49.08	gold quality
smooth muscle tissue	UBERON:0001135	49.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.67

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.