THAP6-AS1

Summary

THAP6-AS1 (THAP6 antisense RNA 1, HGNC:58818) is a long non-coding RNA gene on chromosome 4q21.1.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58818
Approved symbol	THAP6-AS1
Name	THAP6 antisense RNA 1
Location	4q21.1
Locus type	RNA, long non-coding
Status	Approved
Entrez	124900717

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000988410 (4:75541420 A>G), RS1002169425 (4:75540461 T>A), RS1003017354 (4:75539434 G>A), RS1005198545 (4:75540585 G>C,T), RS1005821470 (4:75541854 G>C), RS1008364376 (4:75540355 C>T), RS1008481874 (4:75540809 G>A), RS1008799483 (4:75542351 A>G), RS1009679717 (4:75540515 A>C,G), RS1009956534 (4:75540820 C>T), RS1010031346 (4:75539373 G>A), RS1011771123 (4:75540889 C>T), RS1012126133 (4:75541308 A>G), RS1012952831 (4:75541970 A>G), RS1013774618 (4:75542181 A>G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.