THBS1-AS1

Summary

THBS1-AS1 (THBS1 antisense RNA 1, HGNC:55224) is a long non-coding RNA gene on chromosome 15q14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55224
Approved symbol	THBS1-AS1
Name	THBS1 antisense RNA 1
Location	15q14
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000278621
Ensembl biotype	lncRNA
Entrez	118597840
RNAcentral	URS000077D724 — lncRNA, 526 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000616754

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000616754 — 1 exons

Exon	Start	End
ENSE00003724221	39588357	39588882

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 97.49.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of stomach	UBERON:0001199	97.49	gold quality
colonic epithelium	UBERON:0000397	90.75	gold quality
left uterine tube	UBERON:0001303	90.60	gold quality
smooth muscle tissue	UBERON:0001135	88.62	gold quality
vermiform appendix	UBERON:0001154	86.40	gold quality
rectum	UBERON:0001052	86.38	gold quality
gall bladder	UBERON:0002110	86.17	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.07	gold quality
right lung	UBERON:0002167	84.89	gold quality
upper lobe of left lung	UBERON:0008952	84.42	gold quality
omental fat pad	UBERON:0010414	84.08	gold quality
sural nerve	UBERON:0015488	83.93	gold quality
stromal cell of endometrium	CL:0002255	83.14	gold quality
transverse colon	UBERON:0001157	80.60	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	80.08	gold quality
lung	UBERON:0002048	79.99	gold quality
tonsil	UBERON:0002372	79.57	gold quality
adipose tissue	UBERON:0001013	79.49	gold quality
tibial nerve	UBERON:0001323	79.47	gold quality
colon	UBERON:0001155	79.31	gold quality
mucosa of transverse colon	UBERON:0004991	79.00	gold quality
muscle layer of sigmoid colon	UBERON:0035805	78.82	gold quality
muscle tissue	UBERON:0002385	78.45	gold quality
minor salivary gland	UBERON:0001830	78.16	gold quality
bone marrow cell	CL:0002092	78.12	gold quality
thoracic mammary gland	UBERON:0005200	78.07	gold quality
saliva-secreting gland	UBERON:0001044	77.33	gold quality
intestine	UBERON:0000160	76.83	gold quality
bone marrow	UBERON:0002371	76.45	gold quality
urinary bladder	UBERON:0001255	75.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	8.76

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.