THBS1-IT1

Summary

THBS1-IT1 (THBS1 intronic transcript 1, HGNC:55225) is a long non-coding RNA gene on chromosome 15q14.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55225
Approved symbol	THBS1-IT1
Name	THBS1 intronic transcript 1
Location	15q14
Locus type	RNA, long non-coding
Status	Approved
Aliases	TBULC
Ensembl gene	ENSG00000276107
Ensembl biotype	lncRNA
Entrez	118597829
RNAcentral	URS00026A1C20 — lncRNA, 1128 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000478845

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000478845 — 1 exons

Exon	Start	End
ENSE00001889980	39586561	39587293

Expression profiles

Bgee: expression breadth ubiquitous, 190 present calls, max score 93.13.

Top tissues by expression

283 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of stomach	UBERON:0001199	93.13	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	91.45	gold quality
colonic epithelium	UBERON:0000397	91.15	gold quality
sural nerve	UBERON:0015488	89.86	gold quality
stromal cell of endometrium	CL:0002255	87.19	gold quality
gall bladder	UBERON:0002110	86.80	gold quality
tibial nerve	UBERON:0001323	84.55	gold quality
upper lobe of left lung	UBERON:0008952	84.08	gold quality
rectum	UBERON:0001052	83.50	gold quality
omental fat pad	UBERON:0010414	82.88	gold quality
peritoneum	UBERON:0002358	82.84	gold quality
upper lobe of lung	UBERON:0008948	81.93	gold quality
calcaneal tendon	UBERON:0003701	81.82	gold quality
minor salivary gland	UBERON:0001830	81.71	gold quality
left uterine tube	UBERON:0001303	81.56	gold quality
superficial temporal artery	UBERON:0001614	81.44	gold quality
metanephros cortex	UBERON:0010533	81.02	gold quality
smooth muscle tissue	UBERON:0001135	80.90	gold quality
adipose tissue of abdominal region	UBERON:0007808	80.57	gold quality
body of uterus	UBERON:0009853	80.25	gold quality
lower esophagus mucosa	UBERON:0035834	79.60	gold quality
right lung	UBERON:0002167	78.86	gold quality
vermiform appendix	UBERON:0001154	78.52	gold quality
muscle layer of sigmoid colon	UBERON:0035805	77.99	gold quality
left ovary	UBERON:0002119	77.66	gold quality
caecum	UBERON:0001153	76.85	gold quality
mouth mucosa	UBERON:0003729	76.29	gold quality
left coronary artery	UBERON:0001626	75.71	gold quality
saliva-secreting gland	UBERON:0001044	75.66	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	74.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	12.99

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.