THBS2-AS1

Summary

THBS2-AS1 (THBS2 antisense RNA 1, HGNC:56059) is a long non-coding RNA gene on chromosome 6q27.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56059
Approved symbol	THBS2-AS1
Name	THBS2 antisense RNA 1
Location	6q27
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226445
Ensembl biotype	lncRNA
Entrez	101929523
RNAcentral	URS0000A774CD — lncRNA, 1022 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000444188, ENST00000660724, ENST00000670651, ENST00000796857, ENST00000796858, ENST00000796859, ENST00000796860

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000444188 — 3 exons

Exon	Start	End
ENSE00001739686	169214174	169214487
ENSE00004182918	169239225	169241399
ENSE00004182921	169213154	169213578

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 97.17.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right coronary artery	UBERON:0001625	97.17	gold quality
ascending aorta	UBERON:0001496	96.72	gold quality
thoracic aorta	UBERON:0001515	96.44	gold quality
descending thoracic aorta	UBERON:0002345	95.62	gold quality
left coronary artery	UBERON:0001626	94.19	gold quality
ectocervix	UBERON:0012249	91.75	gold quality
calcaneal tendon	UBERON:0003701	91.70	gold quality
endocervix	UBERON:0000458	90.51	gold quality
skin of abdomen	UBERON:0001416	89.98	gold quality
zone of skin	UBERON:0000014	89.28	gold quality
skin of leg	UBERON:0001511	89.18	gold quality
omental fat pad	UBERON:0010414	88.94	gold quality
tibial artery	UBERON:0007610	88.61	gold quality
popliteal artery	UBERON:0002250	88.52	gold quality
adipose tissue	UBERON:0001013	88.43	gold quality
subcutaneous adipose tissue	UBERON:0002190	88.38	gold quality
body of uterus	UBERON:0009853	88.36	gold quality
thoracic mammary gland	UBERON:0005200	88.17	gold quality
uterine cervix	UBERON:0000002	88.10	gold quality
myometrium	UBERON:0001296	87.28	gold quality
left uterine tube	UBERON:0001303	87.23	gold quality
vagina	UBERON:0000996	86.43	gold quality
tibial nerve	UBERON:0001323	85.87	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	83.91	gold quality
left ovary	UBERON:0002119	83.80	gold quality
right ovary	UBERON:0002118	83.76	gold quality
substantia nigra	UBERON:0002038	83.37	gold quality
putamen	UBERON:0001874	83.10	gold quality
ovary	UBERON:0000992	83.06	gold quality
colonic epithelium	UBERON:0000397	83.04	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	18.97
E-ANND-3	yes	4.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.