THBS4-AS1

Summary

THBS4-AS1 (THBS4 antisense RNA 1, HGNC:40583) is a long non-coding RNA gene on chromosome 5q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40583
Approved symbol	THBS4-AS1
Name	THBS4 antisense RNA 1
Location	5q14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249825
Ensembl biotype	lncRNA
Entrez	101929215
RNAcentral	URS000075AF0C — lncRNA, 2716 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000503007, ENST00000514042, ENST00000661210, ENST00000665368, ENST00000799170, ENST00000799171

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000503007 — 4 exons

Exon	Start	End
ENSE00002038488	80082360	80082404
ENSE00002053401	80052374	80052901
ENSE00002064442	80068514	80068774
ENSE00002085662	80080103	80080224

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 91.06.

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
calcaneal tendon	UBERON:0003701	91.06	gold quality
apex of heart	UBERON:0002098	73.54	gold quality
tibial nerve	UBERON:0001323	70.47	gold quality
heart left ventricle	UBERON:0002084	69.55	gold quality
left testis	UBERON:0004533	69.00	gold quality
testis	UBERON:0000473	68.86	gold quality
sural nerve	UBERON:0015488	68.59	gold quality
right testis	UBERON:0004534	68.30	gold quality
smooth muscle tissue	UBERON:0001135	67.77	gold quality
bone marrow	UBERON:0002371	66.26	gold quality
bone marrow cell	CL:0002092	65.92	silver quality
muscle tissue	UBERON:0002385	65.80	gold quality
mucosa of transverse colon	UBERON:0004991	65.44	gold quality
muscle of leg	UBERON:0001383	65.36	gold quality
endometrium	UBERON:0001295	65.23	gold quality
right lobe of liver	UBERON:0001114	65.04	gold quality
gastrocnemius	UBERON:0001388	64.55	gold quality
granulocyte	CL:0000094	63.76	gold quality
ganglionic eminence	UBERON:0004023	63.51	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	63.06	gold quality
minor salivary gland	UBERON:0001830	62.96	gold quality
muscle layer of sigmoid colon	UBERON:0035805	62.80	gold quality
liver	UBERON:0002107	62.73	gold quality
skeletal muscle tissue	UBERON:0001134	62.60	gold quality
lower esophagus mucosa	UBERON:0035834	62.59	gold quality
saliva-secreting gland	UBERON:0001044	62.51	gold quality
leukocyte	CL:0000738	62.44	gold quality
monocyte	CL:0000576	62.43	gold quality
blood	UBERON:0000178	62.26	gold quality
heart	UBERON:0000948	61.70	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.60

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.