THOC7-AS1

Summary

THOC7-AS1 (THOC7 antisense RNA 1, HGNC:41249) is a long non-coding RNA gene on chromosome 3p14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41249
Approved symbol	THOC7-AS1
Name	THOC7 antisense RNA 1
Location	3p14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000240549
Ensembl biotype	lncRNA
Entrez	100874039
RNAcentral	URS00000812BD — lncRNA, 673 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000468961

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000468961 — 2 exons

Exon	Start	End
ENSE00001822598	63860645	63860996
ENSE00001893683	63861499	63861819

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 77.46.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	77.46	silver quality
bone marrow cell	CL:0002092	66.95	silver quality
colonic epithelium	UBERON:0000397	66.37	silver quality
ventricular zone	UBERON:0003053	65.34	gold quality
skeletal muscle tissue	UBERON:0001134	65.33	gold quality
calcaneal tendon	UBERON:0003701	63.11	gold quality
adrenal tissue	UBERON:0018303	62.76	gold quality
bone marrow	UBERON:0002371	60.76	silver quality
monocyte	CL:0000576	59.50	gold quality
corpus callosum	UBERON:0002336	58.05	gold quality
tonsil	UBERON:0002372	57.98	gold quality
blood	UBERON:0000178	57.69	gold quality
liver	UBERON:0002107	55.26	silver quality
placenta	UBERON:0001987	55.01	gold quality
lymph node	UBERON:0000029	54.93	gold quality
endometrium	UBERON:0001295	53.73	gold quality
islet of Langerhans	UBERON:0000006	53.64	gold quality
stromal cell of endometrium	CL:0002255	53.11	silver quality
gall bladder	UBERON:0002110	52.48	gold quality
muscle of leg	UBERON:0001383	52.28	gold quality
primary visual cortex	UBERON:0002436	51.67	gold quality
urinary bladder	UBERON:0001255	51.62	gold quality
kidney	UBERON:0002113	51.56	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	51.48	gold quality
vermiform appendix	UBERON:0001154	50.52	gold quality
prefrontal cortex	UBERON:0000451	50.16	gold quality
hindlimb stylopod muscle	UBERON:0004252	49.49	gold quality
right ovary	UBERON:0002118	49.25	gold quality
ovary	UBERON:0000992	49.20	gold quality
adult mammalian kidney	UBERON:0000082	49.14	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.95

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• THOC7-AS1/OCT1/FSTL1 axis promotes EMT and serves as a therapeutic target in cutaneous squamous cell carcinoma. (PMID:38605354)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.