THRB-AS1

Summary

THRB-AS1 (THRB antisense RNA 1, HGNC:44515) is a long non-coding RNA gene on chromosome 3p24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44515
Approved symbol	THRB-AS1
Name	THRB antisense RNA 1
Location	3p24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228791
Ensembl biotype	lncRNA
Entrez	644990
RNAcentral	URS000075E878 — lncRNA, 885 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000432368, ENST00000438096, ENST00000594183, ENST00000608893, ENST00000609230, ENST00000610876, ENST00000620754, ENST00000627154, ENST00000628911, ENST00000629562, ENST00000630391, ENST00000807231, ENST00000807232, ENST00000807233, ENST00000807234, ENST00000807235, ENST00000807236, ENST00000807237, ENST00000807238, ENST00000807239

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000432368 — 2 exons

Exon	Start	End
ENSE00001617275	24499532	24500342
ENSE00001783932	24494087	24494491

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 88.76.

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	88.76	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.84	gold quality
ventricular zone	UBERON:0003053	73.20	gold quality
skeletal muscle tissue	UBERON:0001134	72.90	gold quality
colonic epithelium	UBERON:0000397	72.86	gold quality
descending thoracic aorta	UBERON:0002345	71.04	gold quality
liver	UBERON:0002107	70.22	gold quality
right lobe of liver	UBERON:0001114	69.76	gold quality
thoracic aorta	UBERON:0001515	69.75	gold quality
ascending aorta	UBERON:0001496	69.73	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.33	gold quality
ganglionic eminence	UBERON:0004023	68.87	gold quality
calcaneal tendon	UBERON:0003701	67.73	gold quality
popliteal artery	UBERON:0002250	67.47	gold quality
tibial artery	UBERON:0007610	67.43	gold quality
cortex of kidney	UBERON:0001225	66.76	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	66.55	gold quality
left coronary artery	UBERON:0001626	65.28	gold quality
left adrenal gland	UBERON:0001234	65.15	gold quality
kidney	UBERON:0002113	65.12	gold quality
left adrenal gland cortex	UBERON:0035825	65.12	gold quality
muscle of leg	UBERON:0001383	65.05	gold quality
adult mammalian kidney	UBERON:0000082	65.03	gold quality
sural nerve	UBERON:0015488	64.87	silver quality
gastrocnemius	UBERON:0001388	64.61	gold quality
prefrontal cortex	UBERON:0000451	64.16	gold quality
right adrenal gland	UBERON:0001233	64.16	gold quality
right coronary artery	UBERON:0001625	64.05	gold quality
right adrenal gland cortex	UBERON:0035827	63.98	gold quality
adrenal gland	UBERON:0002369	63.60	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-CURD-119	yes	34.94
E-ANND-3	no	4.34

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.