THRB-IT1

Summary

THRB-IT1 (THRB intronic transcript 1, HGNC:41390) is a long non-coding RNA gene on chromosome 3p24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41390
Approved symbol	THRB-IT1
Name	THRB intronic transcript 1
Location	3p24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224822
Ensembl biotype	lncRNA
Entrez	100874274
RNAcentral	URS0000117DDE — lncRNA, 1754 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000425296

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000425296 — 2 exons

Exon	Start	End
ENSE00001686657	24455136	24455431
ENSE00001749032	24457977	24459434

Expression profiles

Bgee: expression breadth ubiquitous, 137 present calls, max score 91.27.

Top tissues by expression

202 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	91.27	gold quality
deltoid	UBERON:0001476	78.26	silver quality
oviduct epithelium	UBERON:0004804	75.55	silver quality
tibia	UBERON:0000979	74.94	silver quality
biceps brachii	UBERON:0001507	74.80	silver quality
colonic epithelium	UBERON:0000397	74.32	gold quality
mucosa of paranasal sinus	UBERON:0005030	74.12	gold quality
skeletal muscle tissue of biceps brachii	UBERON:0004502	73.63	silver quality
jejunal mucosa	UBERON:0000399	71.74	silver quality
tibialis anterior	UBERON:0001385	69.32	silver quality
skeletal muscle tissue	UBERON:0001134	68.32	gold quality
bronchial epithelial cell	CL:0002328	67.89	silver quality
pancreatic ductal cell	CL:0002079	67.55	silver quality
Brodmann (1909) area 23	UBERON:0013554	67.41	silver quality
middle temporal gyrus	UBERON:0002771	66.72	silver quality
bronchus	UBERON:0002185	66.65	silver quality
skin of hip	UBERON:0001554	66.46	gold quality
jejunum	UBERON:0002115	66.15	silver quality
endothelial cell	CL:0000115	66.13	gold quality
ileal mucosa	UBERON:0000331	65.54	gold quality
upper leg skin	UBERON:0004262	65.45	gold quality
tendon	UBERON:0000043	64.44	gold quality
layer of synovial tissue	UBERON:0007616	64.30	silver quality
calcaneal tendon	UBERON:0003701	64.16	gold quality
tendon of biceps brachii	UBERON:0008188	64.07	gold quality
primary visual cortex	UBERON:0002436	62.78	gold quality
mucosa of sigmoid colon	UBERON:0004993	62.47	silver quality
urinary bladder	UBERON:0001255	62.19	silver quality
colonic mucosa	UBERON:0000317	61.93	silver quality
fallopian tube	UBERON:0003889	61.59	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.