THSD4-AS1

Summary

THSD4-AS1 (THSD4 antisense RNA 1, HGNC:51420) is a long non-coding RNA gene on chromosome 15q23.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:51420
Approved symbol	THSD4-AS1
Name	THSD4 antisense RNA 1
Location	15q23
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259964
Ensembl biotype	lncRNA
Entrez	101929196
RNAcentral	URS000075CE41 — lncRNA, 815 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 11 lncRNA

ENST00000561571, ENST00000562634, ENST00000564562, ENST00000566268, ENST00000569258, ENST00000653119, ENST00000665266, ENST00000668533, ENST00000748701, ENST00000748703, ENST00000748704

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561571 — 5 exons

Exon	Start	End
ENSE00002594245	71185425	71185506
ENSE00002601654	71172152	71172157
ENSE00002608851	71183106	71183216
ENSE00002623929	71188816	71189029
ENSE00002630242	71147650	71147790

Expression profiles

Bgee: expression breadth ubiquitous, 122 present calls, max score 75.86.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1113 / max 43.0608, expressed in 46 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
150750	0.1113	46

Top tissues by expression

217 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	75.86	gold quality
anterior cingulate cortex	UBERON:0009835	74.97	gold quality
prefrontal cortex	UBERON:0000451	73.49	gold quality
colonic epithelium	UBERON:0000397	71.40	gold quality
ganglionic eminence	UBERON:0004023	70.88	gold quality
Brodmann (1909) area 9	UBERON:0013540	70.79	gold quality
right frontal lobe	UBERON:0002810	70.28	gold quality
amygdala	UBERON:0001876	69.87	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	67.97	gold quality
neocortex	UBERON:0001950	67.83	gold quality
frontal cortex	UBERON:0001870	66.70	gold quality
cerebral cortex	UBERON:0000956	63.71	gold quality
sural nerve	UBERON:0015488	62.41	silver quality
right hemisphere of cerebellum	UBERON:0014890	61.85	gold quality
hindlimb stylopod muscle	UBERON:0004252	61.35	gold quality
monocyte	CL:0000576	60.48	gold quality
nucleus accumbens	UBERON:0001882	59.26	gold quality
ventricular zone	UBERON:0003053	59.06	silver quality
forebrain	UBERON:0001890	58.99	gold quality
brain	UBERON:0000955	57.98	gold quality
temporal lobe	UBERON:0001871	57.95	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	56.90	gold quality
Ammon’s horn	UBERON:0001954	56.72	gold quality
calcaneal tendon	UBERON:0003701	54.86	gold quality
hypothalamus	UBERON:0001898	54.35	gold quality
cerebellar hemisphere	UBERON:0002245	53.63	gold quality
uterine cervix	UBERON:0000002	52.84	silver quality
islet of Langerhans	UBERON:0000006	51.58	gold quality
corpus callosum	UBERON:0002336	51.27	gold quality
gall bladder	UBERON:0002110	51.09	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.42

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.