TIALD

Summary

TIALD (transcript inducer of AURKA lysosomal degradation, HGNC:56938) is a long non-coding RNA gene on chromosome 12q24.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56938
Approved symbol	TIALD
Name	transcript inducer of AURKA lysosomal degradation
Location	12q24.31
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC079360.1
Ensembl gene	ENSG00000256811
Ensembl biotype	lncRNA
Entrez	105370035
RNAcentral	URS0002A69DBF — lncRNA, 1161 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000543848, ENST00000618674, ENST00000750772, ENST00000750773, ENST00000750774, ENST00000750775, ENST00000750776

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000543848 — 3 exons

Exon	Start	End
ENSE00002279635	121856483	121856646
ENSE00002288720	121856259	121856392
ENSE00002289655	121856924	121857059

Expression profiles

Bgee: expression breadth broad, 97 present calls, max score 85.04.

Top tissues by expression

97 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	85.04	gold quality
liver	UBERON:0002107	81.27	gold quality
right testis	UBERON:0004534	74.05	gold quality
left testis	UBERON:0004533	72.64	gold quality
testis	UBERON:0000473	72.02	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.36	gold quality
metanephros cortex	UBERON:0010533	58.91	gold quality
kidney	UBERON:0002113	57.53	gold quality
cortex of kidney	UBERON:0001225	57.00	gold quality
bone marrow	UBERON:0002371	56.92	gold quality
adult mammalian kidney	UBERON:0000082	56.76	gold quality
blood	UBERON:0000178	56.16	gold quality
gall bladder	UBERON:0002110	55.30	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	55.16	gold quality
islet of Langerhans	UBERON:0000006	54.17	gold quality
placenta	UBERON:0001987	54.03	gold quality
monocyte	CL:0000576	53.52	gold quality
muscle of leg	UBERON:0001383	52.88	gold quality
gastrocnemius	UBERON:0001388	51.98	gold quality
multicellular organism	UBERON:0000468	51.52	gold quality
adenohypophysis	UBERON:0002196	51.04	gold quality
left adrenal gland cortex	UBERON:0035825	49.77	gold quality
saliva-secreting gland	UBERON:0001044	49.75	gold quality
prefrontal cortex	UBERON:0000451	49.27	gold quality
urinary bladder	UBERON:0001255	49.10	gold quality
heart left ventricle	UBERON:0002084	48.32	gold quality
thoracic aorta	UBERON:0001515	48.28	gold quality
tonsil	UBERON:0002372	48.12	gold quality
smooth muscle tissue	UBERON:0001135	48.02	gold quality
ascending aorta	UBERON:0001496	48.00	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.32

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.