TIAM1-AS1

Summary

TIAM1-AS1 (TIAM1 antisense RNA 1, HGNC:54361) is a long non-coding RNA gene on chromosome 21q22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54361
Approved symbol	TIAM1-AS1
Name	TIAM1 antisense RNA 1
Location	21q22.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000237594
Ensembl biotype	lncRNA
Entrez	150051
RNAcentral	URS000212321F — lncRNA, 834 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000433071

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433071 — 2 exons

Exon	Start	End
ENSE00001760430	31560017	31560487
ENSE00001780130	31559245	31559595

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 82.32.

Top tissues by expression

203 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.32	gold quality
mucosa of transverse colon	UBERON:0004991	67.98	gold quality
ganglionic eminence	UBERON:0004023	65.49	gold quality
cortical plate	UBERON:0005343	63.87	gold quality
ventricular zone	UBERON:0003053	62.00	gold quality
ectocervix	UBERON:0012249	59.03	gold quality
lymph node	UBERON:0000029	55.60	gold quality
sural nerve	UBERON:0015488	55.06	silver quality
prefrontal cortex	UBERON:0000451	54.26	gold quality
gall bladder	UBERON:0002110	53.33	gold quality
islet of Langerhans	UBERON:0000006	52.23	gold quality
monocyte	CL:0000576	51.75	silver quality
esophagus mucosa	UBERON:0002469	51.55	gold quality
esophagus	UBERON:0001043	51.43	gold quality
vermiform appendix	UBERON:0001154	51.10	gold quality
rectum	UBERON:0001052	49.89	gold quality
right uterine tube	UBERON:0001302	49.86	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.41	gold quality
pancreas	UBERON:0001264	49.34	gold quality
nucleus accumbens	UBERON:0001882	49.32	gold quality
tonsil	UBERON:0002372	49.19	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	48.86	gold quality
right lobe of liver	UBERON:0001114	48.67	silver quality
lower esophagus mucosa	UBERON:0035834	48.56	gold quality
caecum	UBERON:0001153	47.72	gold quality
transverse colon	UBERON:0001157	47.71	gold quality
amygdala	UBERON:0001876	47.23	gold quality
liver	UBERON:0002107	47.03	silver quality
lower esophagus muscularis layer	UBERON:0035833	46.99	gold quality
cerebellar cortex	UBERON:0002129	46.90	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.08

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.