TIPARP-AS1

Summary

TIPARP-AS1 (TIPARP antisense RNA 1, HGNC:41028) is a long non-coding RNA gene on chromosome 3q25.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41028
Approved symbol	TIPARP-AS1
Name	TIPARP antisense RNA 1
Location	3q25.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243926
Ensembl biotype	lncRNA
Entrez	100287227
RNAcentral	URS000075D97E — lncRNA, 2556 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 35 — 35 lncRNA

ENST00000463449, ENST00000472943, ENST00000473352, ENST00000478005, ENST00000488584, ENST00000492937, ENST00000654528, ENST00000664429, ENST00000664482, ENST00000715952, ENST00000716067, ENST00000721660, ENST00000721661, ENST00000721662, ENST00000721663, ENST00000721664, ENST00000721665, ENST00000721666, ENST00000721667, ENST00000721668, ENST00000721669, ENST00000721670, ENST00000721671, ENST00000721672, ENST00000721673, ENST00000721674, ENST00000721675, ENST00000721676, ENST00000721677, ENST00000721678, ENST00000721679, ENST00000721680, ENST00000721681, ENST00000721682, ENST00000721683

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000463449 — 2 exons

Exon	Start	End
ENSE00001831268	156672345	156672870
ENSE00001893073	156671922	156672130

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 94.22.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.2422 / max 38.9323, expressed in 1261 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
45260	3.2422	1261

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	94.22	gold quality
right testis	UBERON:0004534	93.82	gold quality
testis	UBERON:0000473	93.77	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	92.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	90.72	gold quality
monocyte	CL:0000576	81.78	gold quality
leukocyte	CL:0000738	81.39	gold quality
body of pancreas	UBERON:0001150	79.19	gold quality
right lobe of liver	UBERON:0001114	76.12	gold quality
liver	UBERON:0002107	75.73	gold quality
calcaneal tendon	UBERON:0003701	75.70	gold quality
pancreas	UBERON:0001264	75.27	gold quality
cortex of kidney	UBERON:0001225	74.14	gold quality
muscle of leg	UBERON:0001383	74.04	gold quality
bone marrow cell	CL:0002092	73.64	silver quality
gastrocnemius	UBERON:0001388	73.59	gold quality
granulocyte	CL:0000094	73.37	gold quality
duodenum	UBERON:0002114	72.81	gold quality
right lung	UBERON:0002167	72.50	gold quality
bone marrow	UBERON:0002371	72.43	gold quality
skeletal muscle tissue	UBERON:0001134	72.42	gold quality
cortical plate	UBERON:0005343	72.42	gold quality
left adrenal gland cortex	UBERON:0035825	72.11	gold quality
right adrenal gland cortex	UBERON:0035827	71.92	gold quality
right adrenal gland	UBERON:0001233	71.83	gold quality
mucosa of transverse colon	UBERON:0004991	71.68	gold quality
adult mammalian kidney	UBERON:0000082	71.57	gold quality
left adrenal gland	UBERON:0001234	71.56	gold quality
kidney	UBERON:0002113	71.39	gold quality
thyroid gland	UBERON:0002046	70.83	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.34

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Moreover, time course and promoter activity assays suggest that TIPARP and TIPARP-AS1 work in concert to regulate AHR signaling. Collectively, these data show an added level of complexity in the AHR signaling cascade which involves lncRNAs, whose functions remain poorly understood. (PMID:29274782)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.