TLE1-DT

Summary

TLE1-DT (TLE1 divergent transcript, HGNC:55701) is a long non-coding RNA gene on chromosome 9q21.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55701
Approved symbol	TLE1-DT
Name	TLE1 divergent transcript
Location	9q21.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000233926
Ensembl biotype	lncRNA
Entrez	101927502
RNAcentral	URS0000759AE9 — lncRNA, 1463 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000413050, ENST00000437181, ENST00000701091, ENST00000769780, ENST00000769781, ENST00000769782, ENST00000769783, ENST00000769784

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413050 — 2 exons

Exon	Start	End
ENSE00001644806	81747943	81748079
ENSE00001762625	81755042	81755452

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 84.30.

Top tissues by expression

227 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.30	gold quality
cortical plate	UBERON:0005343	67.37	gold quality
ventricular zone	UBERON:0003053	63.06	gold quality
sural nerve	UBERON:0015488	62.71	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	58.17	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.69	gold quality
right ovary	UBERON:0002118	57.49	gold quality
ganglionic eminence	UBERON:0004023	57.03	silver quality
buccal mucosa cell	CL:0002336	56.60	gold quality
monocyte	CL:0000576	55.29	gold quality
left ovary	UBERON:0002119	55.23	gold quality
islet of Langerhans	UBERON:0000006	55.16	gold quality
vermiform appendix	UBERON:0001154	53.71	gold quality
prefrontal cortex	UBERON:0000451	53.01	gold quality
ovary	UBERON:0000992	52.60	gold quality
calcaneal tendon	UBERON:0003701	52.58	silver quality
pancreas	UBERON:0001264	51.65	gold quality
right lobe of liver	UBERON:0001114	51.02	silver quality
smooth muscle tissue	UBERON:0001135	50.87	gold quality
lymph node	UBERON:0000029	50.82	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.77	gold quality
muscle of leg	UBERON:0001383	50.15	gold quality
gall bladder	UBERON:0002110	49.82	gold quality
spinal cord	UBERON:0002240	49.71	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	49.63	gold quality
gastrocnemius	UBERON:0001388	48.88	gold quality
putamen	UBERON:0001874	48.13	gold quality
ectocervix	UBERON:0012249	48.03	gold quality
body of uterus	UBERON:0009853	47.90	gold quality
body of pancreas	UBERON:0001150	47.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.09

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.