TM4SF18-AS1

Summary

TM4SF18-AS1 (TM4SF18 antisense RNA 1, HGNC:56678) is a long non-coding RNA gene on chromosome 3q25.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56678
Approved symbol	TM4SF18-AS1
Name	TM4SF18 antisense RNA 1
Location	3q25.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	AC093001.1
Ensembl gene	ENSG00000244468
Ensembl biotype	lncRNA
Entrez	128193290
RNAcentral	URS00026A1ACC — lncRNA, 653 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000489011, ENST00000778932, ENST00000778933

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000489011 — 2 exons

Exon	Start	End
ENSE00001078029	149333504	149333653
ENSE00001864042	149284782	149285182

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 85.96.

Top tissues by expression

118 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.96	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	82.22	gold quality
bone marrow cell	CL:0002092	71.40	silver quality
sural nerve	UBERON:0015488	70.70	gold quality
thoracic mammary gland	UBERON:0005200	69.47	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.46	gold quality
lymph node	UBERON:0000029	62.21	gold quality
smooth muscle tissue	UBERON:0001135	60.22	gold quality
ganglionic eminence	UBERON:0004023	58.92	gold quality
skeletal muscle tissue	UBERON:0001134	57.99	silver quality
endometrium	UBERON:0001295	55.95	gold quality
bone marrow	UBERON:0002371	55.70	silver quality
islet of Langerhans	UBERON:0000006	55.29	gold quality
duodenum	UBERON:0002114	54.71	gold quality
placenta	UBERON:0001987	54.49	gold quality
gall bladder	UBERON:0002110	54.44	gold quality
prefrontal cortex	UBERON:0000451	54.41	gold quality
prostate gland	UBERON:0002367	54.07	gold quality
blood	UBERON:0000178	54.06	gold quality
muscle of leg	UBERON:0001383	53.54	gold quality
leukocyte	CL:0000738	53.38	gold quality
monocyte	CL:0000576	53.17	gold quality
body of stomach	UBERON:0001161	53.00	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.95	gold quality
vermiform appendix	UBERON:0001154	52.71	gold quality
stomach	UBERON:0000945	52.63	gold quality
skin of abdomen	UBERON:0001416	52.26	gold quality
mucosa of stomach	UBERON:0001199	52.15	gold quality
gastrocnemius	UBERON:0001388	52.01	gold quality
right adrenal gland cortex	UBERON:0035827	51.80	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.15

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.