TM4SF19-AS1

Summary

TM4SF19-AS1 (TM4SF19 antisense RNA 1, HGNC:41085) is a long non-coding RNA gene on chromosome 3q29.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:41085
Approved symbol	TM4SF19-AS1
Name	TM4SF19 antisense RNA 1
Location	3q29
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235897
Ensembl biotype	lncRNA
Entrez	100874214
RNAcentral	URS000075DC9A — lncRNA, 1847 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000420226, ENST00000444939, ENST00000452051

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420226 — 2 exons

Exon	Start	End
ENSE00004079197	196318288	196318437
ENSE00004079198	196323460	196323679

Expression profiles

Bgee: expression breadth ubiquitous, 131 present calls, max score 80.60.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.60	gold quality
right uterine tube	UBERON:0001302	73.50	gold quality
left testis	UBERON:0004533	73.29	gold quality
testis	UBERON:0000473	72.95	gold quality
right testis	UBERON:0004534	72.37	gold quality
bone marrow cell	CL:0002092	68.63	silver quality
colonic epithelium	UBERON:0000397	67.44	silver quality
granulocyte	CL:0000094	65.41	gold quality
lower esophagus mucosa	UBERON:0035834	65.29	gold quality
skeletal muscle tissue	UBERON:0001134	65.04	gold quality
esophagus mucosa	UBERON:0002469	64.29	gold quality
subcutaneous adipose tissue	UBERON:0002190	63.42	gold quality
blood	UBERON:0000178	62.18	gold quality
stromal cell of endometrium	CL:0002255	62.15	gold quality
upper lobe of left lung	UBERON:0008952	61.82	gold quality
adenohypophysis	UBERON:0002196	60.95	gold quality
gastrocnemius	UBERON:0001388	60.84	gold quality
muscle of leg	UBERON:0001383	60.77	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	60.34	gold quality
adipose tissue	UBERON:0001013	60.29	gold quality
bone marrow	UBERON:0002371	60.25	gold quality
sural nerve	UBERON:0015488	59.89	silver quality
thoracic mammary gland	UBERON:0005200	59.85	gold quality
cortex of kidney	UBERON:0001225	59.78	gold quality
left adrenal gland cortex	UBERON:0035825	59.62	gold quality
islet of Langerhans	UBERON:0000006	59.60	gold quality
lung	UBERON:0002048	59.53	gold quality
ectocervix	UBERON:0012249	58.94	gold quality
fallopian tube	UBERON:0003889	58.89	gold quality
urinary bladder	UBERON:0001255	58.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.88

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• TM4SF19-AS1 facilitates the proliferation of lung squamous cell carcinoma by recruiting WDR5 to mediate TM4SF19. (PMID:35987447)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.