TMC5-AS1

Summary

TMC5-AS1 (TMC5 antisense RNA 1, HGNC:58394) is a long non-coding RNA gene on chromosome 16p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58394
Approved symbol	TMC5-AS1
Name	TMC5 antisense RNA 1
Location	16p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260592
Ensembl biotype	lncRNA
Entrez	124903659

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000561762, ENST00000702436, ENST00000805113, ENST00000805114, ENST00000805115, ENST00000805116, ENST00000805117

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000561762 — 3 exons

Exon	Start	End
ENSE00002587295	19486929	19487320
ENSE00004197109	19487824	19487964
ENSE00004197110	19476746	19477080

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 94.22.

Top tissues by expression

117 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
blood	UBERON:0000178	94.22	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.55	gold quality
bone marrow	UBERON:0002371	78.32	gold quality
bone marrow cell	CL:0002092	76.93	gold quality
monocyte	CL:0000576	76.40	gold quality
colonic epithelium	UBERON:0000397	75.13	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	70.66	gold quality
duodenum	UBERON:0002114	67.48	gold quality
body of stomach	UBERON:0001161	65.93	gold quality
placenta	UBERON:0001987	65.73	gold quality
small intestine	UBERON:0002108	64.38	gold quality
stomach	UBERON:0000945	64.21	gold quality
mucosa of transverse colon	UBERON:0004991	63.92	gold quality
minor salivary gland	UBERON:0001830	63.88	gold quality
small intestine Peyer’s patch	UBERON:0003454	63.83	gold quality
saliva-secreting gland	UBERON:0001044	63.72	gold quality
hindlimb stylopod muscle	UBERON:0004252	62.27	gold quality
transverse colon	UBERON:0001157	62.01	gold quality
upper lobe of left lung	UBERON:0008952	61.92	gold quality
intestine	UBERON:0000160	61.19	gold quality
lung	UBERON:0002048	61.13	gold quality
skeletal muscle tissue	UBERON:0001134	60.56	gold quality
colon	UBERON:0001155	59.61	gold quality
gall bladder	UBERON:0002110	59.52	gold quality
rectum	UBERON:0001052	59.43	gold quality
calcaneal tendon	UBERON:0003701	58.98	gold quality
right lung	UBERON:0002167	58.63	gold quality
fundus of stomach	UBERON:0001160	58.03	gold quality
prostate gland	UBERON:0002367	57.33	gold quality
multicellular organism	UBERON:0000468	56.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.75

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.