TMCC1-DT

Summary

TMCC1-DT (TMCC1 divergent transcript, HGNC:49060) is a long non-coding RNA gene on chromosome 3q22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49060
Approved symbol	TMCC1-DT
Name	TMCC1 divergent transcript
Location	3q22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000271270
Ensembl biotype	lncRNA
Entrez	100507032
RNAcentral	URS000075B198 — lncRNA, 3497 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000603884, ENST00000604747, ENST00000605698, ENST00000605830, ENST00000653304, ENST00000671446, ENST00000686063, ENST00000690344, ENST00000840963, ENST00000840964, ENST00000840965, ENST00000840966, ENST00000840967, ENST00000840968

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000603884 — 2 exons

Exon	Start	End
ENSE00003480416	129893871	129893927
ENSE00003539201	129901707	129902205

Expression profiles

Bgee: expression breadth ubiquitous, 136 present calls, max score 89.24.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 3.5375 / max 49.0305, expressed in 1345 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
38567	3.5375	1345

Top tissues by expression

138 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	89.24	gold quality
quadriceps femoris	UBERON:0001377	87.82	gold quality
cerebellar vermis	UBERON:0004720	87.10	gold quality
sural nerve	UBERON:0015488	77.36	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.89	gold quality
endometrium	UBERON:0001295	75.54	gold quality
colonic epithelium	UBERON:0000397	75.34	gold quality
right uterine tube	UBERON:0001302	74.94	gold quality
ventricular zone	UBERON:0003053	74.85	gold quality
ganglionic eminence	UBERON:0004023	72.54	gold quality
superior frontal gyrus	UBERON:0002661	71.55	gold quality
cortical plate	UBERON:0005343	71.12	gold quality
right ovary	UBERON:0002118	70.95	gold quality
ovary	UBERON:0000992	70.73	gold quality
left ovary	UBERON:0002119	70.36	gold quality
adrenal tissue	UBERON:0018303	70.17	gold quality
left adrenal gland cortex	UBERON:0035825	70.04	gold quality
right adrenal gland	UBERON:0001233	69.60	gold quality
anterior cingulate cortex	UBERON:0009835	69.50	gold quality
bone marrow cell	CL:0002092	69.49	silver quality
left adrenal gland	UBERON:0001234	69.26	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.21	gold quality
prefrontal cortex	UBERON:0000451	69.02	gold quality
adrenal gland	UBERON:0002369	68.88	gold quality
right adrenal gland cortex	UBERON:0035827	68.68	gold quality
frontal cortex	UBERON:0001870	68.67	gold quality
cerebral cortex	UBERON:0000956	68.64	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	68.60	gold quality
Brodmann (1909) area 9	UBERON:0013540	68.48	gold quality
right frontal lobe	UBERON:0002810	67.54	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.44

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.