TMCO1-AS1

Summary

TMCO1-AS1 (TMCO1 antisense RNA 1, HGNC:54046) is a long non-coding RNA gene on chromosome 1q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54046
Approved symbol	TMCO1-AS1
Name	TMCO1 antisense RNA 1
Location	1q24.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224358
Ensembl biotype	lncRNA
Entrez	100147773
RNAcentral	URS00007E40F5 — lncRNA, 2148 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000423121

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000423121 — 2 exons

Exon	Start	End
ENSE00001680077	165773474	165775176
ENSE00001789159	165768929	165769375

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 82.44.

FANTOM5 (CAGE): breadth broad, TPM avg 1.3942 / max 54.2742, expressed in 793 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
6395	1.3942	793

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.44	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.52	silver quality
sural nerve	UBERON:0015488	60.48	silver quality
ventricular zone	UBERON:0003053	60.05	gold quality
islet of Langerhans	UBERON:0000006	58.86	gold quality
cortical plate	UBERON:0005343	58.44	silver quality
calcaneal tendon	UBERON:0003701	57.45	gold quality
ganglionic eminence	UBERON:0004023	56.67	gold quality
stromal cell of endometrium	CL:0002255	56.39	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.31	gold quality
lymph node	UBERON:0000029	55.67	gold quality
corpus callosum	UBERON:0002336	54.88	gold quality
skeletal muscle tissue	UBERON:0001134	54.78	silver quality
muscle of leg	UBERON:0001383	53.82	gold quality
adrenal tissue	UBERON:0018303	53.68	gold quality
gastrocnemius	UBERON:0001388	53.39	gold quality
leukocyte	CL:0000738	52.88	silver quality
monocyte	CL:0000576	52.86	silver quality
blood	UBERON:0000178	52.70	silver quality
right uterine tube	UBERON:0001302	52.37	gold quality
endometrium	UBERON:0001295	52.32	gold quality
prefrontal cortex	UBERON:0000451	52.05	gold quality
bone marrow	UBERON:0002371	51.58	silver quality
pancreas	UBERON:0001264	51.27	gold quality
duodenum	UBERON:0002114	50.65	gold quality
pituitary gland	UBERON:0000007	50.48	gold quality
right adrenal gland	UBERON:0001233	50.47	gold quality
vermiform appendix	UBERON:0001154	50.36	gold quality
gall bladder	UBERON:0002110	50.33	gold quality
liver	UBERON:0002107	50.30	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.