TMED2-DT

Summary

TMED2-DT (TMED2 divergent transcript, HGNC:53346) is a long non-coding RNA gene on chromosome 12q24.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:53346
Approved symbol	TMED2-DT
Name	TMED2 divergent transcript
Location	12q24.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247373
Ensembl biotype	lncRNA
Entrez	101927415
RNAcentral	URS00007E4A2D — lncRNA, 2316 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000498967, ENST00000793071, ENST00000793072, ENST00000793073, ENST00000793074, ENST00000793075, ENST00000793076, ENST00000793077, ENST00000793078, ENST00000793079, ENST00000793080, ENST00000793081, ENST00000793082, ENST00000793083, ENST00000793084, ENST00000793085, ENST00000793086, ENST00000793087, ENST00000793088, ENST00000793089

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000498967 — 3 exons

Exon	Start	End
ENSE00001534827	123583601	123583698
ENSE00002224469	123584212	123585115
ENSE00002259901	123575891	123583167

Expression profiles

Bgee: expression breadth ubiquitous, 130 present calls, max score 75.38.

FANTOM5 (CAGE): breadth broad, TPM avg 0.3926 / max 14.3724, expressed in 218 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
133958	0.3926	218

Top tissues by expression

130 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.38	silver quality
bone marrow cell	CL:0002092	66.54	silver quality
colonic epithelium	UBERON:0000397	64.51	silver quality
stromal cell of endometrium	CL:0002255	63.04	gold quality
right uterine tube	UBERON:0001302	61.00	gold quality
right lobe of thyroid gland	UBERON:0001119	60.63	gold quality
mucosa of transverse colon	UBERON:0004991	60.47	gold quality
skeletal muscle tissue	UBERON:0001134	60.16	gold quality
ventricular zone	UBERON:0003053	59.86	silver quality
liver	UBERON:0002107	59.13	gold quality
bone marrow	UBERON:0002371	58.53	silver quality
cortex of kidney	UBERON:0001225	58.43	gold quality
thyroid gland	UBERON:0002046	58.32	gold quality
cortical plate	UBERON:0005343	58.20	silver quality
left lobe of thyroid gland	UBERON:0001120	58.04	gold quality
endometrium	UBERON:0001295	57.98	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.95	gold quality
body of pancreas	UBERON:0001150	57.75	gold quality
muscle tissue	UBERON:0002385	57.54	gold quality
ganglionic eminence	UBERON:0004023	57.24	silver quality
tonsil	UBERON:0002372	56.99	gold quality
right lobe of liver	UBERON:0001114	56.68	gold quality
ovary	UBERON:0000992	56.61	gold quality
apex of heart	UBERON:0002098	56.54	gold quality
left ovary	UBERON:0002119	56.28	gold quality
metanephros cortex	UBERON:0010533	56.18	gold quality
right ovary	UBERON:0002118	56.12	gold quality
uterine cervix	UBERON:0000002	55.97	gold quality
myometrium	UBERON:0001296	55.79	gold quality
adenohypophysis	UBERON:0002196	55.76	gold quality

Single-cell (SCXA)

Detected in 2 experiment(s), a significant marker in 2.

Experiment	Marker?	Max mean expression
E-MTAB-9543	yes	28.18
E-ANND-3	yes	6.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.