TMEM11-DT

Summary

TMEM11-DT (TMEM11 divergent transcript, HGNC:55671) is a long non-coding RNA gene on chromosome 17p11.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55671
Approved symbol	TMEM11-DT
Name	TMEM11 divergent transcript
Location	17p11.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235530
Ensembl biotype	lncRNA
Entrez	107984969
RNAcentral	URS00026A1FFF — lncRNA, 495 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000439136, ENST00000580291, ENST00000661579, ENST00000721266, ENST00000721267, ENST00000721268, ENST00000721269

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000439136 — 3 exons

Exon	Start	End
ENSE00001612954	21229773	21230035
ENSE00001701716	21220365	21220468
ENSE00004040855	21214330	21214450

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 79.86.

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.86	gold quality
colonic epithelium	UBERON:0000397	73.84	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.18	gold quality
bone marrow cell	CL:0002092	69.01	silver quality
sural nerve	UBERON:0015488	66.63	gold quality
skeletal muscle tissue	UBERON:0001134	64.15	gold quality
blood	UBERON:0000178	64.02	gold quality
tonsil	UBERON:0002372	63.98	gold quality
ventricular zone	UBERON:0003053	63.57	gold quality
endometrium	UBERON:0001295	63.44	gold quality
corpus callosum	UBERON:0002336	63.13	gold quality
gastrocnemius	UBERON:0001388	63.04	gold quality
muscle of leg	UBERON:0001383	63.00	gold quality
muscle tissue	UBERON:0002385	62.73	gold quality
cortical plate	UBERON:0005343	62.66	gold quality
calcaneal tendon	UBERON:0003701	62.13	gold quality
ganglionic eminence	UBERON:0004023	62.10	gold quality
monocyte	CL:0000576	61.98	gold quality
leukocyte	CL:0000738	61.61	gold quality
mucosa of transverse colon	UBERON:0004991	61.34	gold quality
bone marrow	UBERON:0002371	61.30	silver quality
hindlimb stylopod muscle	UBERON:0004252	60.76	gold quality
adrenal tissue	UBERON:0018303	60.70	gold quality
stromal cell of endometrium	CL:0002255	60.32	gold quality
cortex of kidney	UBERON:0001225	60.20	gold quality
metanephros cortex	UBERON:0010533	60.08	gold quality
myometrium	UBERON:0001296	59.70	gold quality
kidney	UBERON:0002113	59.27	gold quality
thyroid gland	UBERON:0002046	59.14	gold quality
uterine cervix	UBERON:0000002	59.10	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.73

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.