TMEM123-DT

Summary

TMEM123-DT (TMEM123 divergent transcript, HGNC:55502) is a long non-coding RNA gene on chromosome 11q22.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55502
Approved symbol	TMEM123-DT
Name	TMEM123 divergent transcript
Location	11q22.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255337
Ensembl biotype	lncRNA
Entrez	101928424
RNAcentral	URS0000A764DE — lncRNA, 759 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000528717, ENST00000769469, ENST00000769470, ENST00000769471, ENST00000769472

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000528717 — 2 exons

Exon	Start	End
ENSE00004130644	102452860	102453049
ENSE00004130647	102461448	102462045

Expression profiles

Bgee: expression breadth ubiquitous, 215 present calls, max score 85.16.

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.16	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.28	gold quality
right uterine tube	UBERON:0001302	84.19	gold quality
sural nerve	UBERON:0015488	82.57	gold quality
tendon of biceps brachii	UBERON:0008188	81.91	silver quality
epithelial cell of pancreas	CL:0000083	78.85	silver quality
right lobe of liver	UBERON:0001114	76.95	gold quality
endothelial cell	CL:0000115	76.46	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	76.27	gold quality
bronchial epithelial cell	CL:0002328	76.10	gold quality
bronchus	UBERON:0002185	75.39	gold quality
buccal mucosa cell	CL:0002336	75.29	silver quality
spinal cord	UBERON:0002240	74.90	gold quality
medial globus pallidus	UBERON:0002477	74.61	gold quality
oviduct epithelium	UBERON:0004804	74.16	gold quality
substantia nigra	UBERON:0002038	73.91	gold quality
mucosa of paranasal sinus	UBERON:0005030	73.57	silver quality
amygdala	UBERON:0001876	73.07	gold quality
midbrain	UBERON:0001891	72.46	gold quality
globus pallidus	UBERON:0001875	71.81	gold quality
thyroid gland	UBERON:0002046	71.74	gold quality
hypothalamus	UBERON:0001898	71.64	gold quality
sperm	CL:0000019	71.47	silver quality
right lobe of thyroid gland	UBERON:0001119	70.98	gold quality
left lobe of thyroid gland	UBERON:0001120	70.88	gold quality
right adrenal gland cortex	UBERON:0035827	70.69	gold quality
tibial nerve	UBERON:0001323	70.68	gold quality
oocyte	CL:0000023	70.59	gold quality
liver	UBERON:0002107	70.51	gold quality
germinal epithelium of ovary	UBERON:0001304	70.44	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.89

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.