TMEM14B-DT

Summary

TMEM14B-DT (TMEM14B divergent transcript, HGNC:55230) is a long non-coding RNA gene on chromosome 6p24.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55230
Approved symbol	TMEM14B-DT
Name	TMEM14B divergent transcript
Location	6p24.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000272097
Ensembl biotype	lncRNA
Entrez	118597831
RNAcentral	URS00026A1A3D — lncRNA, 916 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000606522, ENST00000606652, ENST00000659819, ENST00000765575

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000606522 — 2 exons

Exon	Start	End
ENSE00003694828	10747461	10747569
ENSE00003698888	10743324	10744314

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 89.41.

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	89.41	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.47	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	83.04	gold quality
buccal mucosa cell	CL:0002336	79.00	silver quality
left testis	UBERON:0004533	77.09	gold quality
right testis	UBERON:0004534	75.82	gold quality
testis	UBERON:0000473	74.41	gold quality
cerebellar hemisphere	UBERON:0002245	71.34	gold quality
right hemisphere of cerebellum	UBERON:0014890	71.30	gold quality
cerebellar cortex	UBERON:0002129	71.23	gold quality
right adrenal gland	UBERON:0001233	69.77	gold quality
cerebellum	UBERON:0002037	69.13	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.73	gold quality
adenohypophysis	UBERON:0002196	67.66	gold quality
right frontal lobe	UBERON:0002810	67.51	gold quality
right adrenal gland cortex	UBERON:0035827	67.44	gold quality
stromal cell of endometrium	CL:0002255	67.24	gold quality
pituitary gland	UBERON:0000007	66.87	gold quality
mucosa of transverse colon	UBERON:0004991	66.46	gold quality
right uterine tube	UBERON:0001302	66.27	gold quality
nucleus accumbens	UBERON:0001882	66.22	gold quality
left adrenal gland	UBERON:0001234	66.21	gold quality
anterior cingulate cortex	UBERON:0009835	65.79	gold quality
ventricular zone	UBERON:0003053	65.51	gold quality
islet of Langerhans	UBERON:0000006	65.48	gold quality
left adrenal gland cortex	UBERON:0035825	65.02	gold quality
hypothalamus	UBERON:0001898	64.87	gold quality
lymph node	UBERON:0000029	64.63	gold quality
adrenal gland	UBERON:0002369	64.32	gold quality
caudate nucleus	UBERON:0001873	64.27	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.58

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.