TMEM154-AS1

Summary

TMEM154-AS1 (TMEM154 antisense RNA 1, HGNC:58413) is a long non-coding RNA gene on chromosome 4q31.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58413
Approved symbol	TMEM154-AS1
Name	TMEM154 antisense RNA 1
Location	4q31.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248571
Ensembl biotype	lncRNA
Entrez	141731991

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000515789

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000515789 — 2 exons

Exon	Start	End
ENSE00002037966	152666368	152667028
ENSE00002064518	152668398	152670107

Expression profiles

Bgee: expression breadth broad, 50 present calls, max score 78.49.

Top tissues by expression

50 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow cell	CL:0002092	78.49	gold quality
uterine cervix	UBERON:0000002	68.98	gold quality
bone marrow	UBERON:0002371	66.79	gold quality
tonsil	UBERON:0002372	66.23	gold quality
lymph node	UBERON:0000029	61.28	gold quality
blood	UBERON:0000178	60.09	gold quality
vermiform appendix	UBERON:0001154	58.78	gold quality
urinary bladder	UBERON:0001255	57.64	gold quality
rectum	UBERON:0001052	52.87	gold quality
monocyte	CL:0000576	50.90	silver quality
spleen	UBERON:0002106	50.53	gold quality
ectocervix	UBERON:0012249	50.25	gold quality
duodenum	UBERON:0002114	49.54	gold quality
Ammon’s horn	UBERON:0001954	46.92	silver quality
small intestine	UBERON:0002108	46.10	gold quality
gall bladder	UBERON:0002110	46.09	silver quality
lower esophagus muscularis layer	UBERON:0035833	45.85	gold quality
small intestine Peyer’s patch	UBERON:0003454	45.77	gold quality
intestine	UBERON:0000160	45.70	gold quality
adrenal gland	UBERON:0002369	45.42	silver quality
esophagus	UBERON:0001043	45.20	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	45.11	gold quality
omental fat pad	UBERON:0010414	45.03	gold quality
colon	UBERON:0001155	45.00	gold quality
ascending aorta	UBERON:0001496	44.59	gold quality
islet of Langerhans	UBERON:0000006	44.52	silver quality
adipose tissue	UBERON:0001013	44.48	gold quality
prefrontal cortex	UBERON:0000451	44.10	silver quality
muscle layer of sigmoid colon	UBERON:0035805	43.60	gold quality
zone of skin	UBERON:0000014	43.29	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.59

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.