TMEM167B-DT

Summary

TMEM167B-DT (TMEM167B divergent transcript, HGNC:55076) is a long non-coding RNA gene on chromosome 1p13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55076
Approved symbol	TMEM167B-DT
Name	TMEM167B divergent transcript
Location	1p13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000273382
Ensembl biotype	lncRNA
Entrez	105378892
RNAcentral	URS000021F608 — lncRNA, 2888 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000608574

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000608574 — 1 exons

Exon	Start	End
ENSE00003703141	109087971	109090858

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 81.83.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8954 / max 52.1378, expressed in 487 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
13669	0.8954	487

Top tissues by expression

236 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.83	gold quality
buccal mucosa cell	CL:0002336	71.30	silver quality
secondary oocyte	CL:0000655	69.99	gold quality
sperm	CL:0000019	69.79	gold quality
bone marrow cell	CL:0002092	66.17	silver quality
stromal cell of endometrium	CL:0002255	65.87	gold quality
tibia	UBERON:0000979	63.16	silver quality
islet of Langerhans	UBERON:0000006	62.46	gold quality
parietal pleura	UBERON:0002400	61.78	gold quality
visceral pleura	UBERON:0002401	61.48	gold quality
esophagus squamous epithelium	UBERON:0006920	60.98	silver quality
amniotic fluid	UBERON:0000173	60.77	gold quality
right atrium auricular region	UBERON:0006631	60.17	gold quality
ventricular zone	UBERON:0003053	59.78	silver quality
cardiac atrium	UBERON:0002081	59.66	gold quality
monocyte	CL:0000576	59.42	gold quality
granulocyte	CL:0000094	59.39	gold quality
leukocyte	CL:0000738	59.35	gold quality
adenohypophysis	UBERON:0002196	59.10	gold quality
cortical plate	UBERON:0005343	58.78	gold quality
ganglionic eminence	UBERON:0004023	58.55	gold quality
right lobe of liver	UBERON:0001114	58.36	gold quality
smooth muscle tissue	UBERON:0001135	58.25	gold quality
pituitary gland	UBERON:0000007	57.95	gold quality
mucosa of stomach	UBERON:0001199	57.57	gold quality
left adrenal gland	UBERON:0001234	57.33	gold quality
blood	UBERON:0000178	57.29	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.28	gold quality
right adrenal gland cortex	UBERON:0035827	57.21	gold quality
germinal epithelium of ovary	UBERON:0001304	57.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.