TMEM220-AS1

Summary

TMEM220-AS1 (TMEM220 antisense RNA 1, HGNC:44357) is a long non-coding RNA gene on chromosome 17p13.1-p12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44357
Approved symbol	TMEM220-AS1
Name	TMEM220 antisense RNA 1
Location	17p13.1-p12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000263400
Ensembl biotype	lncRNA
Entrez	101101775
RNAcentral	URS000075D7DF — lncRNA, 738 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 50 — 50 lncRNA

ENST00000579114, ENST00000580899, ENST00000581366, ENST00000581910, ENST00000583012, ENST00000583115, ENST00000583343, ENST00000584714, ENST00000585243, ENST00000645807, ENST00000647474, ENST00000664973, ENST00000742812, ENST00000742813, ENST00000742814, ENST00000742815, ENST00000742816, ENST00000742817, ENST00000742818, ENST00000742819, ENST00000742820, ENST00000742821, ENST00000742822, ENST00000742823, ENST00000742824, ENST00000742825, ENST00000742826, ENST00000742827, ENST00000742828, ENST00000742829, ENST00000742830, ENST00000742831, ENST00000742832, ENST00000743030, ENST00000743031, ENST00000743032, ENST00000743033, ENST00000743034, ENST00000743035, ENST00000743036, ENST00000743037, ENST00000743038, ENST00000743039, ENST00000743269, ENST00000743270, ENST00000743271, ENST00000743272, ENST00000743273, ENST00000743274, ENST00000743275

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000579114 — 4 exons

Exon	Start	End
ENSE00002698106	10766679	10766856
ENSE00002701539	10754229	10754362
ENSE00004081064	10729787	10729900
ENSE00004081066	10767865	10769071

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 91.90.

FANTOM5 (CAGE): breadth broad, TPM avg 1.3866 / max 54.2742, expressed in 691 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
159594	1.3866	691

Top tissues by expression

137 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	91.90	gold quality
liver	UBERON:0002107	90.97	gold quality
cerebellar vermis	UBERON:0004720	88.72	gold quality
quadriceps femoris	UBERON:0001377	88.43	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	86.55	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.94	gold quality
body of stomach	UBERON:0001161	81.31	gold quality
fundus of stomach	UBERON:0001160	80.64	gold quality
right adrenal gland	UBERON:0001233	80.60	gold quality
stomach	UBERON:0000945	80.40	gold quality
right adrenal gland cortex	UBERON:0035827	80.15	gold quality
rectum	UBERON:0001052	79.29	gold quality
left adrenal gland	UBERON:0001234	78.84	gold quality
left adrenal gland cortex	UBERON:0035825	78.51	gold quality
duodenum	UBERON:0002114	77.80	gold quality
adrenal gland	UBERON:0002369	77.67	gold quality
sural nerve	UBERON:0015488	77.55	gold quality
transverse colon	UBERON:0001157	77.45	gold quality
small intestine	UBERON:0002108	77.25	gold quality
small intestine Peyer’s patch	UBERON:0003454	77.09	gold quality
prostate gland	UBERON:0002367	76.71	gold quality
mucosa of stomach	UBERON:0001199	76.57	gold quality
gastrocnemius	UBERON:0001388	76.44	gold quality
muscle of leg	UBERON:0001383	76.43	gold quality
left ovary	UBERON:0002119	75.95	gold quality
gall bladder	UBERON:0002110	75.83	gold quality
intestine	UBERON:0000160	75.58	gold quality
ovary	UBERON:0000992	75.58	gold quality
thymus	UBERON:0002370	75.39	silver quality
right ovary	UBERON:0002118	75.30	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.27

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.