TMEM252-DT

Summary

TMEM252-DT (TMEM252 divergent transcript, HGNC:54377) is a long non-coding RNA gene on chromosome 9q21.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54377
Approved symbol	TMEM252-DT
Name	TMEM252 divergent transcript
Location	9q21.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226337
Ensembl biotype	lncRNA
Entrez	105376072
RNAcentral	URS00026A2780 — lncRNA, 1758 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000413269, ENST00000763204, ENST00000763205

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000413269 — 5 exons

Exon	Start	End
ENSE00001609752	68541036	68541230
ENSE00001675866	68625641	68625847
ENSE00001713460	68633039	68633260
ENSE00001786756	68542378	68542642
ENSE00003704108	68643593	68644442

Expression profiles

Bgee: expression breadth broad, 52 present calls, max score 73.74.

Top tissues by expression

165 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	73.74	silver quality
sperm	CL:0000019	71.78	silver quality
adult mammalian kidney	UBERON:0000082	58.90	gold quality
oviduct epithelium	UBERON:0004804	57.80	silver quality
leukocyte	CL:0000738	56.23	silver quality
right uterine tube	UBERON:0001302	55.34	gold quality
fallopian tube	UBERON:0003889	54.64	gold quality
kidney	UBERON:0002113	53.37	gold quality
blood	UBERON:0000178	53.01	gold quality
cortex of kidney	UBERON:0001225	48.62	gold quality
anterior cingulate cortex	UBERON:0009835	48.22	silver quality
metanephros cortex	UBERON:0010533	47.49	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	47.33	gold quality
buccal mucosa cell	CL:0002336	46.89	gold quality
skin of hip	UBERON:0001554	46.85	gold quality
lower esophagus muscularis layer	UBERON:0035833	46.82	gold quality
gall bladder	UBERON:0002110	46.62	silver quality
gastrocnemius	UBERON:0001388	45.68	silver quality
esophagus	UBERON:0001043	45.64	gold quality
metanephros	UBERON:0000081	45.30	gold quality
upper leg skin	UBERON:0004262	45.25	silver quality
tibial artery	UBERON:0007610	45.00	gold quality
vermiform appendix	UBERON:0001154	44.98	silver quality
endometrium	UBERON:0001295	44.82	gold quality
aorta	UBERON:0000947	44.49	gold quality
anatomical system	UBERON:0000467	43.91	gold quality
material anatomical entity	UBERON:0000465	43.75	gold quality
multicellular organism	UBERON:0000468	43.69	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	43.68	gold quality
uterus	UBERON:0000995	43.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.79

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.