TMEM263-DT

Summary

TMEM263-DT (TMEM263 divergent transcript, HGNC:55395) is a long non-coding RNA gene on chromosome 12q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55395
Approved symbol	TMEM263-DT
Name	TMEM263 divergent transcript
Location	12q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000260329
Ensembl biotype	lncRNA
Entrez	119863870
RNAcentral	URS00026A2656 — lncRNA, 1983 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000570282

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000570282 — 1 exons

Exon	Start	End
ENSE00004155767	106953513	106955705

Expression profiles

Bgee: expression breadth ubiquitous, 178 present calls, max score 85.26.

Top tissues by expression

238 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.26	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.00	gold quality
endothelial cell	CL:0000115	74.03	silver quality
apex of heart	UBERON:0002098	73.33	gold quality
right atrium auricular region	UBERON:0006631	73.16	gold quality
pituitary gland	UBERON:0000007	72.66	gold quality
islet of Langerhans	UBERON:0000006	72.33	gold quality
body of uterus	UBERON:0009853	72.27	gold quality
calcaneal tendon	UBERON:0003701	72.23	gold quality
adenohypophysis	UBERON:0002196	72.20	gold quality
cortical plate	UBERON:0005343	72.08	gold quality
tibial nerve	UBERON:0001323	71.86	gold quality
cardiac atrium	UBERON:0002081	71.60	gold quality
popliteal artery	UBERON:0002250	71.22	gold quality
tibial artery	UBERON:0007610	71.20	gold quality
heart left ventricle	UBERON:0002084	71.16	gold quality
ganglionic eminence	UBERON:0004023	70.81	gold quality
cardiac ventricle	UBERON:0002082	70.79	gold quality
muscle layer of sigmoid colon	UBERON:0035805	70.71	gold quality
right coronary artery	UBERON:0001625	70.65	gold quality
muscle of leg	UBERON:0001383	70.40	gold quality
hindlimb stylopod muscle	UBERON:0004252	70.33	gold quality
heart	UBERON:0000948	70.31	gold quality
gastrocnemius	UBERON:0001388	70.14	gold quality
lower esophagus muscularis layer	UBERON:0035833	70.06	gold quality
lower esophagus	UBERON:0013473	70.02	gold quality
aorta	UBERON:0000947	69.59	gold quality
right hemisphere of cerebellum	UBERON:0014890	69.52	gold quality
left coronary artery	UBERON:0001626	69.46	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	69.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.34

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.