TMEM269-DT

Summary

TMEM269-DT (TMEM269 divergent transcript, HGNC:54423) is a long non-coding RNA gene on chromosome 1p34.2.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:54423
Approved symbol	TMEM269-DT
Name	TMEM269 divergent transcript
Location	1p34.2
Locus type	RNA, long non-coding
Status	Approved
Entrez	105378683
RNAcentral	URS00028539CC — lncRNA, 852 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 1 (showing top): chr1p34

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000260002 (1:42786555 C>T), RS1000418913 (1:42786627 G>A,T), RS1000661304 (1:42782330 C>G,T), RS1000713395 (1:42782509 C>G), RS1001742224 (1:42781463 G>A), RS1001866536 (1:42781125 G>T), RS1002194308 (1:42781308 G>A,T), RS1002593046 (1:42776431 T>C), RS1002777390 (1:42779267 C>CTCGGGAGGCTGAGGCAGGAGAATG), RS1003255859 (1:42782223 G>A,C), RS1003698096 (1:42777382 T>G), RS1003708838 (1:42777426 C>A,T), RS1004179104 (1:42780768 T>C), RS1004252250 (1:42779775 G>A,C), RS1004347539 (1:42785785 C>T)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.