TMEM30A-DT

Summary

TMEM30A-DT (TMEM30A divergent transcript, HGNC:48985) is a long non-coding RNA gene on chromosome 6q14.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48985
Approved symbol	TMEM30A-DT
Name	TMEM30A divergent transcript
Location	6q14.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225793
Ensembl biotype	lncRNA
Entrez	100506804
RNAcentral	URS000075E4A4 — lncRNA, 1297 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000438676, ENST00000607221, ENST00000607799, ENST00000655404, ENST00000657244, ENST00000657787, ENST00000661161, ENST00000685742, ENST00000689068, ENST00000701185, ENST00000745887, ENST00000745888, ENST00000745889, ENST00000745890, ENST00000745891, ENST00000745892, ENST00000745894, ENST00000745896, ENST00000745897

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438676 — 3 exons

Exon	Start	End
ENSE00001642870	75293493	75293594
ENSE00004086209	75296521	75296908
ENSE00004086227	75284998	75285309

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 79.61.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 4.5402 / max 78.2988, expressed in 1526 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
68618	2.9015	1289
68619	1.1722	671
68620	0.4665	225

Top tissues by expression

134 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.61	gold quality
sural nerve	UBERON:0015488	76.36	gold quality
calcaneal tendon	UBERON:0003701	74.64	gold quality
skeletal muscle tissue	UBERON:0001134	71.53	gold quality
ventricular zone	UBERON:0003053	70.59	gold quality
islet of Langerhans	UBERON:0000006	70.41	gold quality
hindlimb stylopod muscle	UBERON:0004252	69.81	gold quality
muscle tissue	UBERON:0002385	69.47	gold quality
popliteal artery	UBERON:0002250	69.08	gold quality
tibial artery	UBERON:0007610	69.07	gold quality
heart left ventricle	UBERON:0002084	68.83	gold quality
gastrocnemius	UBERON:0001388	68.70	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.47	gold quality
muscle of leg	UBERON:0001383	68.16	gold quality
heart	UBERON:0000948	67.83	gold quality
colonic epithelium	UBERON:0000397	67.46	silver quality
apex of heart	UBERON:0002098	67.12	gold quality
right atrium auricular region	UBERON:0006631	66.59	gold quality
descending thoracic aorta	UBERON:0002345	66.53	gold quality
bone marrow cell	CL:0002092	66.45	silver quality
ascending aorta	UBERON:0001496	66.41	gold quality
thoracic aorta	UBERON:0001515	66.40	gold quality
cortical plate	UBERON:0005343	65.98	gold quality
pancreas	UBERON:0001264	65.95	gold quality
right uterine tube	UBERON:0001302	65.64	gold quality
urinary bladder	UBERON:0001255	65.45	gold quality
monocyte	CL:0000576	65.43	gold quality
adrenal tissue	UBERON:0018303	65.42	gold quality
ganglionic eminence	UBERON:0004023	65.41	gold quality
leukocyte	CL:0000738	65.02	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.94

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.