TMEM33-DT

Summary

TMEM33-DT (TMEM33 divergent transcript, HGNC:58779) is a long non-coding RNA gene on chromosome 4p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:58779
Approved symbol	TMEM33-DT
Name	TMEM33 divergent transcript
Location	4p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249771
Ensembl biotype	lncRNA
Entrez	105374426

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000510772, ENST00000660525, ENST00000716833, ENST00000716834, ENST00000716835, ENST00000716836, ENST00000716837, ENST00000716838, ENST00000716839

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000510772 — 3 exons

Exon	Start	End
ENSE00002022145	41894531	41894579
ENSE00002046646	41892443	41892583
ENSE00003877878	41883060	41883694

Expression profiles

Bgee: expression breadth broad, 93 present calls, max score 80.47.

Top tissues by expression

93 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.47	silver quality
monocyte	CL:0000576	70.46	gold quality
leukocyte	CL:0000738	69.54	gold quality
skeletal muscle tissue	UBERON:0001134	63.62	silver quality
ganglionic eminence	UBERON:0004023	63.55	gold quality
ventricular zone	UBERON:0003053	62.05	gold quality
endometrium	UBERON:0001295	58.97	silver quality
vermiform appendix	UBERON:0001154	58.18	gold quality
liver	UBERON:0002107	54.11	gold quality
myometrium	UBERON:0001296	53.39	gold quality
islet of Langerhans	UBERON:0000006	52.67	gold quality
blood	UBERON:0000178	52.32	silver quality
right lobe of liver	UBERON:0001114	51.73	gold quality
granulocyte	CL:0000094	51.63	gold quality
lymph node	UBERON:0000029	51.15	silver quality
caudate nucleus	UBERON:0001873	50.48	gold quality
pancreas	UBERON:0001264	50.30	gold quality
cortex of kidney	UBERON:0001225	49.45	gold quality
adrenal tissue	UBERON:0018303	49.00	silver quality
urinary bladder	UBERON:0001255	47.81	gold quality
superior frontal gyrus	UBERON:0002661	47.60	silver quality
gall bladder	UBERON:0002110	46.80	silver quality
muscle of leg	UBERON:0001383	46.57	silver quality
gastrocnemius	UBERON:0001388	46.22	silver quality
mucosa of transverse colon	UBERON:0004991	45.89	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	45.67	silver quality
lung	UBERON:0002048	45.61	gold quality
adult mammalian kidney	UBERON:0000082	45.48	silver quality
placenta	UBERON:0001987	45.38	silver quality
prefrontal cortex	UBERON:0000451	45.33	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.