TMEM51-AS1

Summary

TMEM51-AS1 (TMEM51 antisense RNA 1, HGNC:26301) is a long non-coding RNA gene on chromosome 1p36.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26301
Approved symbol	TMEM51-AS1
Name	TMEM51 antisense RNA 1
Location	1p36.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ23703
Ensembl gene	ENSG00000175147
Ensembl biotype	lncRNA
Entrez	200197
RNAcentral	URS000075CC67 — lncRNA, 6979 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000310916, ENST00000404665, ENST00000650369, ENST00000660005, ENST00000667108, ENST00000669314

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000310916 — 6 exons

Exon	Start	End
ENSE00001210444	15152291	15152464
ENSE00001361043	15111815	15117807
ENSE00001361051	15120577	15120697
ENSE00001610917	15120972	15121059
ENSE00001625985	15124228	15124373
ENSE00001790059	15118327	15118904

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 88.04.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0368 / max 6.6423, expressed in 15 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
10435	0.0292	15
10434	0.0076	3

Top tissues by expression

251 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cerebellar hemisphere	UBERON:0002245	88.04	gold quality
right hemisphere of cerebellum	UBERON:0014890	87.94	gold quality
cerebellar cortex	UBERON:0002129	87.88	gold quality
cerebellum	UBERON:0002037	86.73	gold quality
body of pancreas	UBERON:0001150	84.69	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	82.69	gold quality
pancreas	UBERON:0001264	79.65	gold quality
body of stomach	UBERON:0001161	76.59	gold quality
metanephros cortex	UBERON:0010533	75.04	gold quality
left ovary	UBERON:0002119	74.80	gold quality
stomach	UBERON:0000945	74.69	gold quality
right ovary	UBERON:0002118	74.69	gold quality
mucosa of stomach	UBERON:0001199	74.31	gold quality
gall bladder	UBERON:0002110	73.53	gold quality
spleen	UBERON:0002106	72.45	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.23	gold quality
ventricular zone	UBERON:0003053	72.00	gold quality
islet of Langerhans	UBERON:0000006	71.72	gold quality
cortical plate	UBERON:0005343	71.43	gold quality
vagina	UBERON:0000996	71.37	gold quality
fundus of stomach	UBERON:0001160	70.53	gold quality
ovary	UBERON:0000992	70.44	gold quality
right adrenal gland cortex	UBERON:0035827	70.38	gold quality
ectocervix	UBERON:0012249	69.83	gold quality
amygdala	UBERON:0001876	69.78	gold quality
lower esophagus mucosa	UBERON:0035834	69.74	gold quality
putamen	UBERON:0001874	69.52	gold quality
left adrenal gland cortex	UBERON:0035825	69.08	gold quality
urinary bladder	UBERON:0001255	69.05	gold quality
right uterine tube	UBERON:0001302	68.87	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.84

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.