TMEM78

Summary

TMEM78 (transmembrane protein 78, HGNC:32307) is a long non-coding RNA gene on chromosome 1q42.13.

Predicted to be located in membrane.

Source: NCBI Gene 677790 — RefSeq curated summary.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:32307
Approved symbol	TMEM78
Name	transmembrane protein 78
Location	1q42.13
Locus type	gene with protein product
Status	Approved
Aliases	FLJ40168
Ensembl gene	ENSG00000177800
Ensembl biotype	lncRNA
Entrez	677790

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000323223

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000323223 — 1 exons

Exon	Start	End
ENSE00001264754	229249636	229251810

Expression profiles

Bgee: expression breadth broad, 87 present calls, max score 78.27.

Top tissues by expression

87 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	78.27	silver quality
ventricular zone	UBERON:0003053	58.08	silver quality
cortical plate	UBERON:0005343	57.62	silver quality
ganglionic eminence	UBERON:0004023	57.24	gold quality
hindlimb stylopod muscle	UBERON:0004252	56.31	silver quality
monocyte	CL:0000576	54.90	gold quality
stromal cell of endometrium	CL:0002255	52.21	silver quality
calcaneal tendon	UBERON:0003701	51.62	silver quality
liver	UBERON:0002107	50.88	silver quality
muscle of leg	UBERON:0001383	48.35	silver quality
gastrocnemius	UBERON:0001388	48.03	gold quality
islet of Langerhans	UBERON:0000006	47.17	silver quality
blood	UBERON:0000178	47.15	silver quality
prefrontal cortex	UBERON:0000451	46.80	silver quality
placenta	UBERON:0001987	46.20	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	46.02	silver quality
right lobe of liver	UBERON:0001114	45.87	silver quality
vermiform appendix	UBERON:0001154	45.68	silver quality
endometrium	UBERON:0001295	44.92	silver quality
superior frontal gyrus	UBERON:0002661	44.59	silver quality
lymph node	UBERON:0000029	44.49	silver quality
adult mammalian kidney	UBERON:0000082	44.41	silver quality
pancreas	UBERON:0001264	43.67	silver quality
primary visual cortex	UBERON:0002436	43.63	silver quality
body of pancreas	UBERON:0001150	42.53	silver quality
adrenal tissue	UBERON:0018303	42.32	silver quality
tibial artery	UBERON:0007610	42.22	silver quality
heart left ventricle	UBERON:0002084	41.83	silver quality
right hemisphere of cerebellum	UBERON:0014890	41.82	silver quality
esophagus mucosa	UBERON:0002469	41.55	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.