TMLHE-AS1

Summary

TMLHE-AS1 (TMLHE antisense RNA 1, HGNC:44261) is a long non-coding RNA gene on chromosome Xq28.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44261
Approved symbol	TMLHE-AS1
Name	TMLHE antisense RNA 1
Location	Xq28
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224533
Ensembl biotype	lncRNA
Entrez	100507404
RNAcentral	URS000001A014 — lncRNA, 1702 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000433624, ENST00000447347, ENST00000452506, ENST00000717381, ENST00000717382, ENST00000833578, ENST00000833579, ENST00000833580, ENST00000833581, ENST00000833582, ENST00000833583, ENST00000833584, ENST00000833585, ENST00000833586, ENST00000833587, ENST00000833588, ENST00000833589, ENST00000833590, ENST00000833591, ENST00000833592

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000433624 — 4 exons

Exon	Start	End
ENSE00001658569	155466540	155466849
ENSE00001730773	155474539	155474601
ENSE00001742827	155492880	155494110
ENSE00001774189	155489292	155489389

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 84.53.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.53	gold quality
corpus callosum	UBERON:0002336	81.89	gold quality
bone marrow cell	CL:0002092	77.52	gold quality
blood	UBERON:0000178	70.01	gold quality
bone marrow	UBERON:0002371	68.38	gold quality
monocyte	CL:0000576	66.83	gold quality
sural nerve	UBERON:0015488	66.42	gold quality
leukocyte	CL:0000738	66.23	gold quality
cortical plate	UBERON:0005343	66.03	gold quality
calcaneal tendon	UBERON:0003701	63.59	gold quality
skeletal muscle tissue	UBERON:0001134	61.84	gold quality
adrenal tissue	UBERON:0018303	61.69	gold quality
tonsil	UBERON:0002372	60.68	gold quality
liver	UBERON:0002107	59.84	gold quality
ganglionic eminence	UBERON:0004023	59.23	gold quality
spleen	UBERON:0002106	58.87	gold quality
right lung	UBERON:0002167	58.76	gold quality
ventricular zone	UBERON:0003053	58.39	silver quality
left ovary	UBERON:0002119	57.72	gold quality
ovary	UBERON:0000992	57.55	gold quality
lymph node	UBERON:0000029	57.50	gold quality
muscle tissue	UBERON:0002385	57.23	gold quality
granulocyte	CL:0000094	57.08	gold quality
kidney	UBERON:0002113	56.97	gold quality
cortex of kidney	UBERON:0001225	56.95	gold quality
right adrenal gland cortex	UBERON:0035827	56.54	gold quality
right adrenal gland	UBERON:0001233	56.26	gold quality
right lobe of liver	UBERON:0001114	56.17	gold quality
adrenal gland	UBERON:0002369	56.16	gold quality
urinary bladder	UBERON:0001255	55.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.