TMPRSS6-AS1

Summary

TMPRSS6-AS1 (TMPRSS6 antisense RNA 1, HGNC:40775) is a long non-coding RNA gene on chromosome 22q12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40775
Approved symbol	TMPRSS6-AS1
Name	TMPRSS6 antisense RNA 1
Location	22q12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231467
Ensembl biotype	lncRNA
Entrez	141585749

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000414203

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414203 — 3 exons

Exon	Start	End
ENSE00001644997	37082657	37082847
ENSE00001734659	37080068	37080260
ENSE00001790360	37082479	37082558

Expression profiles

Bgee: expression breadth broad, 66 present calls, max score 79.36.

Top tissues by expression

66 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	79.36	gold quality
liver	UBERON:0002107	70.67	gold quality
right lobe of liver	UBERON:0001114	69.39	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	65.24	gold quality
duodenum	UBERON:0002114	61.14	gold quality
right lobe of thyroid gland	UBERON:0001119	58.97	gold quality
bone marrow	UBERON:0002371	57.15	gold quality
monocyte	CL:0000576	56.28	gold quality
islet of Langerhans	UBERON:0000006	56.24	gold quality
lymph node	UBERON:0000029	56.13	gold quality
rectum	UBERON:0001052	55.86	gold quality
gall bladder	UBERON:0002110	55.85	gold quality
tonsil	UBERON:0002372	55.45	gold quality
vermiform appendix	UBERON:0001154	55.19	gold quality
kidney	UBERON:0002113	53.87	gold quality
granulocyte	CL:0000094	53.85	gold quality
adenohypophysis	UBERON:0002196	53.74	gold quality
pituitary gland	UBERON:0000007	53.10	gold quality
gastrocnemius	UBERON:0001388	52.11	gold quality
blood	UBERON:0000178	51.41	silver quality
left ovary	UBERON:0002119	51.04	gold quality
small intestine	UBERON:0002108	49.80	gold quality
pancreas	UBERON:0001264	48.83	gold quality
zone of skin	UBERON:0000014	47.55	gold quality
skin of abdomen	UBERON:0001416	47.55	gold quality
skin of leg	UBERON:0001511	47.43	gold quality
fallopian tube	UBERON:0003889	46.90	gold quality
multicellular organism	UBERON:0000468	46.56	gold quality
right atrium auricular region	UBERON:0006631	46.31	gold quality
caudate nucleus	UBERON:0001873	45.94	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.66

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.