TNFRSF14-AS1

Summary

TNFRSF14-AS1 (TNFRSF14 antisense RNA 1, HGNC:26966) is a long non-coding RNA gene on chromosome 1p36.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26966
Approved symbol	TNFRSF14-AS1
Name	TNFRSF14 antisense RNA 1
Location	1p36.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	ENST00000416860.2
Ensembl gene	ENSG00000238164
Ensembl biotype	lncRNA
Entrez	115110
RNAcentral	URS000075A9D9 — lncRNA, 4619 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 19 — 19 lncRNA

ENST00000416860, ENST00000432521, ENST00000443892, ENST00000448624, ENST00000449660, ENST00000452793, ENST00000829787, ENST00000829788, ENST00000829789, ENST00000829790, ENST00000829791, ENST00000829792, ENST00000829793, ENST00000829794, ENST00000829795, ENST00000829796, ENST00000829797, ENST00000829798, ENST00000829799

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416860 — 6 exons

Exon	Start	End
ENSE00001678711	2549920	2550119
ENSE00001686392	2551775	2552703
ENSE00001731480	2554101	2554296
ENSE00001765907	2553626	2553814
ENSE00004243593	2556977	2557059
ENSE00004243597	2554724	2556696

Expression profiles

Bgee: expression breadth ubiquitous, 132 present calls, max score 96.15.

FANTOM5 (CAGE): breadth broad, TPM avg 1.5931 / max 73.7226, expressed in 431 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
9921	1.0938	354
9922	0.2282	121
9919	0.1526	69
9920	0.1185	41

Top tissues by expression

132 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
duodenum	UBERON:0002114	96.15	gold quality
mucosa of transverse colon	UBERON:0004991	95.11	gold quality
small intestine Peyer’s patch	UBERON:0003454	91.52	gold quality
small intestine	UBERON:0002108	91.42	gold quality
transverse colon	UBERON:0001157	90.22	gold quality
spleen	UBERON:0002106	87.38	gold quality
granulocyte	CL:0000094	87.09	gold quality
metanephros cortex	UBERON:0010533	85.32	gold quality
intestine	UBERON:0000160	85.18	gold quality
rectum	UBERON:0001052	84.29	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	84.16	gold quality
blood	UBERON:0000178	84.12	gold quality
cortex of kidney	UBERON:0001225	84.06	gold quality
right uterine tube	UBERON:0001302	83.82	gold quality
apex of heart	UBERON:0002098	83.58	gold quality
colon	UBERON:0001155	82.88	gold quality
vermiform appendix	UBERON:0001154	82.19	gold quality
bone marrow	UBERON:0002371	81.45	gold quality
right lobe of liver	UBERON:0001114	81.20	gold quality
upper lobe of left lung	UBERON:0008952	81.13	gold quality
body of stomach	UBERON:0001161	81.11	gold quality
endocervix	UBERON:0000458	80.64	gold quality
lymph node	UBERON:0000029	80.29	gold quality
right adrenal gland cortex	UBERON:0035827	79.43	gold quality
stomach	UBERON:0000945	79.41	gold quality
kidney	UBERON:0002113	79.19	gold quality
adult mammalian kidney	UBERON:0000082	79.08	gold quality
prostate gland	UBERON:0002367	78.68	gold quality
gall bladder	UBERON:0002110	78.54	gold quality
liver	UBERON:0002107	78.42	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.