TNPO1-DT

Summary

TNPO1-DT (TNPO1 divergent transcript, HGNC:40328) is a long non-coding RNA gene on chromosome 5q13.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40328
Approved symbol	TNPO1-DT
Name	TNPO1 divergent transcript
Location	5q13.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000249085
Ensembl biotype	lncRNA
Entrez	121232377
RNAcentral	URS00026A240B — lncRNA, 5139 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 23 — 23 lncRNA

ENST00000506250, ENST00000506293, ENST00000507957, ENST00000508217, ENST00000512573, ENST00000513767, ENST00000659888, ENST00000662691, ENST00000663630, ENST00000800006, ENST00000800007, ENST00000800008, ENST00000800009, ENST00000800010, ENST00000800011, ENST00000800012, ENST00000800013, ENST00000800014, ENST00000800015, ENST00000800016, ENST00000800017, ENST00000800018, ENST00000800019

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000506250 — 3 exons

Exon	Start	End
ENSE00002041619	72580812	72580977
ENSE00002062701	72574752	72574852
ENSE00002071104	72574186	72574509

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 83.37.

Top tissues by expression

116 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.37	gold quality
cortical plate	UBERON:0005343	73.80	gold quality
ventricular zone	UBERON:0003053	69.24	gold quality
bone marrow cell	CL:0002092	65.79	silver quality
hindlimb stylopod muscle	UBERON:0004252	64.76	gold quality
skeletal muscle tissue	UBERON:0001134	64.11	gold quality
testis	UBERON:0000473	62.82	gold quality
left testis	UBERON:0004533	62.77	gold quality
right testis	UBERON:0004534	62.43	gold quality
lymph node	UBERON:0000029	62.31	gold quality
muscle of leg	UBERON:0001383	60.31	gold quality
prefrontal cortex	UBERON:0000451	59.72	gold quality
gastrocnemius	UBERON:0001388	59.06	gold quality
bone marrow	UBERON:0002371	58.92	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	56.91	gold quality
islet of Langerhans	UBERON:0000006	56.53	gold quality
right uterine tube	UBERON:0001302	55.76	gold quality
duodenum	UBERON:0002114	55.42	gold quality
frontal cortex	UBERON:0001870	54.96	gold quality
calcaneal tendon	UBERON:0003701	54.91	silver quality
primary visual cortex	UBERON:0002436	54.12	gold quality
monocyte	CL:0000576	53.64	silver quality
anterior cingulate cortex	UBERON:0009835	53.30	gold quality
cerebral cortex	UBERON:0000956	52.89	gold quality
superior frontal gyrus	UBERON:0002661	52.74	gold quality
right coronary artery	UBERON:0001625	52.46	gold quality
rectum	UBERON:0001052	52.35	gold quality
gall bladder	UBERON:0002110	52.31	gold quality
liver	UBERON:0002107	52.26	gold quality
nucleus accumbens	UBERON:0001882	51.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.97

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.