TNRC17

Summary

TNRC17 (trinucleotide repeat containing 17, HGNC:11961) is a long non-coding RNA gene on chromosome 2q21.3.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:11961
Approved symbol	TNRC17
Name	trinucleotide repeat containing 17
Location	2q21.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	CAGL234
Entrez	27321
RNAcentral	URS0000BC4455 — lncRNA, 4182 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000079506 (2:235513934 T>C), RS1000190538 (2:235517968 C>T), RS1000278327 (2:235518986 G>C), RS1000667206 (2:235517648 A>C,G), RS1001139668 (2:235514786 G>A), RS1001520227 (2:235515029 A>G), RS1001740351 (2:235518095 G>A), RS1003175620 (2:235514362 A>G), RS1003208197 (2:235514162 G>GCGCA,GCGCACA,GCGCACACA,GCGCACACACA,GCGCACACACACA,GCGCACACACACACA,GCGCGCA,GCGCGCACA,GCGCGCGCA), RS1003769241 (2:235519326 G>T), RS1003808196 (2:235516642 T>C), RS1004196336 (2:235519629 T>A), RS1004306444 (2:235516647 C>T), RS1004658119 (2:235514831 CG>C), RS1005133943 (2:235514652 G>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Smoke	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.