TNRC6B-DT

Summary

TNRC6B-DT (TNRC6B divergent transcript, HGNC:55373) is a long non-coding RNA gene on chromosome 22q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55373
Approved symbol	TNRC6B-DT
Name	TNRC6B divergent transcript
Location	22q13.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000261202
Ensembl biotype	lncRNA
Entrez	114841040
RNAcentral	URS0000EEACB1 — lncRNA, 1401 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000569912, ENST00000845443

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000569912 — 1 exons

Exon	Start	End
ENSE00004272816	40042688	40044586

Expression profiles

Bgee: expression breadth broad, 100 present calls, max score 88.11.

FANTOM5 (CAGE): breadth broad, TPM avg 0.8380 / max 41.4998, expressed in 371 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
194302	0.2959	133
194303	0.2585	101
194304	0.2454	108
194305	0.0382	12

Top tissues by expression

192 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	88.11	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.92	gold quality
left testis	UBERON:0004533	74.89	gold quality
right testis	UBERON:0004534	73.51	gold quality
testis	UBERON:0000473	73.20	gold quality
bone marrow cell	CL:0002092	68.79	silver quality
secondary oocyte	CL:0000655	62.04	gold quality
ganglionic eminence	UBERON:0004023	61.41	gold quality
lower lobe of lung	UBERON:0008949	59.60	silver quality
vagina	UBERON:0000996	58.24	gold quality
adult organism	UBERON:0007023	56.69	silver quality
hindlimb stylopod muscle	UBERON:0004252	56.10	silver quality
islet of Langerhans	UBERON:0000006	55.68	gold quality
granulocyte	CL:0000094	55.52	gold quality
pancreas	UBERON:0001264	53.28	gold quality
monocyte	CL:0000576	53.03	silver quality
prefrontal cortex	UBERON:0000451	51.27	gold quality
ectocervix	UBERON:0012249	50.55	gold quality
lower esophagus mucosa	UBERON:0035834	50.06	gold quality
vermiform appendix	UBERON:0001154	49.49	gold quality
upper leg skin	UBERON:0004262	49.48	silver quality
cerebellar vermis	UBERON:0004720	48.93	gold quality
right lobe of liver	UBERON:0001114	48.82	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	47.70	gold quality
lymph node	UBERON:0000029	47.31	gold quality
uterine cervix	UBERON:0000002	47.17	silver quality
muscle of leg	UBERON:0001383	47.05	gold quality
gall bladder	UBERON:0002110	46.94	gold quality
lateral nuclear group of thalamus	UBERON:0002736	46.87	gold quality
thymus	UBERON:0002370	46.30	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.85

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.