TNS1-AS1

Summary

TNS1-AS1 (TNS1 antisense RNA 1, HGNC:40589) is a long non-coding RNA gene on chromosome 2q35.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40589
Approved symbol	TNS1-AS1
Name	TNS1 antisense RNA 1
Location	2q35
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000223923
Ensembl biotype	lncRNA
Entrez	105373878
RNAcentral	URS00001C30D5 — lncRNA, 568 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 5 — 5 lncRNA

ENST00000450996, ENST00000654642, ENST00000728390, ENST00000728391, ENST00000728392

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000450996 — 4 exons

Exon	Start	End
ENSE00001652877	217978707	217978844
ENSE00001669299	217992403	217992615
ENSE00001673674	217986835	217986933
ENSE00002503473	217985464	217985581

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 83.03.

Top tissues by expression

129 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	83.03	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	78.48	silver quality
left ovary	UBERON:0002119	75.24	gold quality
ovary	UBERON:0000992	74.39	gold quality
right ovary	UBERON:0002118	71.93	gold quality
left lobe of thyroid gland	UBERON:0001120	71.01	gold quality
thyroid gland	UBERON:0002046	70.96	gold quality
apex of heart	UBERON:0002098	70.50	gold quality
body of uterus	UBERON:0009853	70.13	gold quality
myometrium	UBERON:0001296	69.92	gold quality
right lobe of thyroid gland	UBERON:0001119	69.91	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	69.65	gold quality
metanephros cortex	UBERON:0010533	69.41	gold quality
adult mammalian kidney	UBERON:0000082	68.19	gold quality
right uterine tube	UBERON:0001302	67.99	gold quality
left uterine tube	UBERON:0001303	67.87	gold quality
cortex of kidney	UBERON:0001225	67.83	gold quality
right lung	UBERON:0002167	67.83	gold quality
fallopian tube	UBERON:0003889	67.56	gold quality
kidney	UBERON:0002113	66.87	gold quality
fundus of stomach	UBERON:0001160	66.23	gold quality
ventricular zone	UBERON:0003053	65.65	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	65.64	gold quality
mucosa of stomach	UBERON:0001199	65.41	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.36	gold quality
lower esophagus	UBERON:0013473	65.31	gold quality
muscle layer of sigmoid colon	UBERON:0035805	65.24	gold quality
popliteal artery	UBERON:0002250	65.11	gold quality
tibial artery	UBERON:0007610	65.11	gold quality
colonic epithelium	UBERON:0000397	65.03	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.53

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.