TNS2-AS1

Summary

TNS2-AS1 (TNS2 antisense RNA 1, HGNC:27464) is a long non-coding RNA gene on chromosome 12q13.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27464
Approved symbol	TNS2-AS1
Name	TNS2 antisense RNA 1
Location	12q13.13
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP11-983P16.4
Ensembl gene	ENSG00000257337
Ensembl biotype	lncRNA
Entrez	283335
RNAcentral	URS0000611D31 — lncRNA, 2863 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 83 — 83 lncRNA

ENST00000546566, ENST00000546767, ENST00000546793, ENST00000549388, ENST00000550601, ENST00000551890, ENST00000552905, ENST00000607643, ENST00000653826, ENST00000654457, ENST00000656120, ENST00000657514, ENST00000657729, ENST00000658354, ENST00000660006, ENST00000662446, ENST00000662887, ENST00000662901, ENST00000663863, ENST00000666649, ENST00000667771, ENST00000668380, ENST00000669379, ENST00000670565, ENST00000684981, ENST00000685842, ENST00000686638, ENST00000688419, ENST00000700826, ENST00000701213, ENST00000701531, ENST00000701905, ENST00000701964, ENST00000732094, ENST00000732095, ENST00000732096, ENST00000732097, ENST00000732098, ENST00000732099, ENST00000732100, ENST00000732101, ENST00000732102, ENST00000732103, ENST00000732104, ENST00000732105, ENST00000732106, ENST00000732107, ENST00000732108, ENST00000732109, ENST00000732110, ENST00000732111, ENST00000732112, ENST00000732113, ENST00000732114, ENST00000732115, ENST00000732116, ENST00000732117, ENST00000732118, ENST00000732119, ENST00000732120, ENST00000732121, ENST00000732122, ENST00000732123, ENST00000732124, ENST00000732125, ENST00000732126, ENST00000732127, ENST00000732128, ENST00000732129, ENST00000732130, ENST00000732131, ENST00000732132, ENST00000732133, ENST00000732134, ENST00000732135, ENST00000732136, ENST00000732137, ENST00000732138, ENST00000732139, ENST00000732140, ENST00000732141, ENST00000732142, ENST00000732143

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000546566 — 4 exons

Exon	Start	End
ENSE00002347533	53045961	53046061
ENSE00002375864	53045600	53045653
ENSE00003934882	53038963	53040263
ENSE00004062138	53046853	53047072

Expression profiles

Bgee: expression breadth ubiquitous, 162 present calls, max score 96.50.

Top tissues by expression

256 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of stomach	UBERON:0001199	96.50	gold quality
tibial artery	UBERON:0007610	95.38	gold quality
popliteal artery	UBERON:0002250	95.37	gold quality
tibial nerve	UBERON:0001323	94.87	gold quality
aorta	UBERON:0000947	94.31	gold quality
pancreatic ductal cell	CL:0002079	94.09	silver quality
right coronary artery	UBERON:0001625	94.08	gold quality
sural nerve	UBERON:0015488	93.35	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	93.32	gold quality
ascending aorta	UBERON:0001496	93.28	gold quality
thoracic aorta	UBERON:0001515	93.24	gold quality
descending thoracic aorta	UBERON:0002345	92.94	gold quality
left coronary artery	UBERON:0001626	92.82	gold quality
coronary artery	UBERON:0001621	91.67	gold quality
adrenal tissue	UBERON:0018303	91.67	gold quality
spinal cord	UBERON:0002240	91.08	gold quality
right ovary	UBERON:0002118	90.40	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	90.31	gold quality
endocervix	UBERON:0000458	90.22	gold quality
left ovary	UBERON:0002119	90.22	gold quality
ectocervix	UBERON:0012249	89.72	gold quality
calcaneal tendon	UBERON:0003701	89.59	gold quality
left uterine tube	UBERON:0001303	89.23	gold quality
right adrenal gland cortex	UBERON:0035827	88.89	gold quality
right lung	UBERON:0002167	88.55	gold quality
subcutaneous adipose tissue	UBERON:0002190	88.48	gold quality
right adrenal gland	UBERON:0001233	88.45	gold quality
left adrenal gland cortex	UBERON:0035825	88.41	gold quality
lower esophagus muscularis layer	UBERON:0035833	88.22	gold quality
lower esophagus	UBERON:0013473	88.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.13

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.