TOMM22-DT

Summary

TOMM22-DT (TOMM22 divergent transcript, HGNC:56758) is a long non-coding RNA gene on chromosome 22q13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:56758
Approved symbol	TOMM22-DT
Name	TOMM22 divergent transcript
Location	22q13.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	lnc408
Ensembl gene	ENSG00000228274
Ensembl biotype	lncRNA
Entrez	124905117
RNAcentral	URS0000EF46B9 — lncRNA, 1737 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000412067, ENST00000422408, ENST00000431924, ENST00000444381, ENST00000653554, ENST00000656432, ENST00000666365

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412067 — 2 exons

Exon	Start	End
ENSE00001603193	38675814	38676489
ENSE00001760769	38681726	38681787

Expression profiles

Bgee: expression breadth ubiquitous, 159 present calls, max score 81.01.

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.01	gold quality
ganglionic eminence	UBERON:0004023	80.55	gold quality
stromal cell of endometrium	CL:0002255	80.28	gold quality
left ovary	UBERON:0002119	79.49	gold quality
right hemisphere of cerebellum	UBERON:0014890	79.45	gold quality
cerebellar hemisphere	UBERON:0002245	79.29	gold quality
cerebellar cortex	UBERON:0002129	79.26	gold quality
right ovary	UBERON:0002118	78.93	gold quality
apex of heart	UBERON:0002098	78.76	gold quality
metanephros cortex	UBERON:0010533	78.00	gold quality
ventricular zone	UBERON:0003053	77.86	gold quality
skin of abdomen	UBERON:0001416	77.30	gold quality
adenohypophysis	UBERON:0002196	77.30	gold quality
skin of leg	UBERON:0001511	77.16	gold quality
body of uterus	UBERON:0009853	77.11	gold quality
body of pancreas	UBERON:0001150	77.08	gold quality
cortical plate	UBERON:0005343	77.08	gold quality
right uterine tube	UBERON:0001302	77.01	gold quality
cerebellum	UBERON:0002037	76.66	gold quality
sural nerve	UBERON:0015488	75.36	gold quality
endocervix	UBERON:0000458	74.86	gold quality
pituitary gland	UBERON:0000007	74.77	gold quality
ectocervix	UBERON:0012249	74.73	gold quality
ovary	UBERON:0000992	74.63	gold quality
hindlimb stylopod muscle	UBERON:0004252	74.35	gold quality
muscle layer of sigmoid colon	UBERON:0035805	74.22	gold quality
right lobe of thyroid gland	UBERON:0001119	74.15	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	74.12	gold quality
minor salivary gland	UBERON:0001830	74.02	gold quality
left uterine tube	UBERON:0001303	73.97	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.63

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.