TOX-DT

Summary

TOX-DT (TOX divergent transcript, HGNC:55935) is a long non-coding RNA gene on chromosome 8q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55935
Approved symbol	TOX-DT
Name	TOX divergent transcript
Location	8q12.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000167912
Ensembl biotype	lncRNA
Entrez	100505501
RNAcentral	URS0000BC45C6 — lncRNA, 3219 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000517898, ENST00000518993, ENST00000523683, ENST00000662685, ENST00000665670, ENST00000685620, ENST00000688120, ENST00000800312, ENST00000800313, ENST00000800314, ENST00000800315, ENST00000800316, ENST00000800317, ENST00000800318

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000517898 — 2 exons

Exon	Start	End
ENSE00002091411	59120336	59121315
ENSE00002125581	59119946	59120071

Expression profiles

Bgee: expression breadth ubiquitous, 175 present calls, max score 90.03.

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	90.03	gold quality
ventricular zone	UBERON:0003053	87.65	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.00	gold quality
thymus	UBERON:0002370	82.50	gold quality
anterior cingulate cortex	UBERON:0009835	82.11	gold quality
ganglionic eminence	UBERON:0004023	81.82	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	81.25	gold quality
granulocyte	CL:0000094	80.97	gold quality
Brodmann (1909) area 9	UBERON:0013540	80.56	gold quality
right frontal lobe	UBERON:0002810	80.08	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	79.25	gold quality
sural nerve	UBERON:0015488	79.22	gold quality
amygdala	UBERON:0001876	79.20	gold quality
prefrontal cortex	UBERON:0000451	78.55	gold quality
muscle layer of sigmoid colon	UBERON:0035805	78.14	gold quality
neocortex	UBERON:0001950	78.11	gold quality
frontal cortex	UBERON:0001870	77.02	gold quality
islet of Langerhans	UBERON:0000006	76.09	gold quality
cerebral cortex	UBERON:0000956	76.07	gold quality
hypothalamus	UBERON:0001898	75.83	gold quality
rectum	UBERON:0001052	75.82	gold quality
body of stomach	UBERON:0001161	75.26	gold quality
transverse colon	UBERON:0001157	74.50	gold quality
mucosa of transverse colon	UBERON:0004991	74.27	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	74.11	gold quality
ileal mucosa	UBERON:0000331	74.09	gold quality
mucosa of stomach	UBERON:0001199	74.01	gold quality
lower esophagus muscularis layer	UBERON:0035833	74.01	gold quality
lower esophagus	UBERON:0013473	73.97	gold quality
caudate nucleus	UBERON:0001873	73.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.68

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.