TP73-AS2

Summary

TP73-AS2 (TP73 antisense RNA 2, HGNC:40591) is a long non-coding RNA gene on chromosome 1p36.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:40591
Approved symbol	TP73-AS2
Name	TP73 antisense RNA 2
Location	1p36.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	RP5-1092A11.2
Ensembl gene	ENSG00000235131
Ensembl biotype	lncRNA
Entrez	117134600
RNAcentral	URS00000D9E9B — lncRNA, 351 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000416554

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000416554 — 2 exons

Exon	Start	End
ENSE00001679378	3712200	3712438
ENSE00001735702	3714187	3714298

Expression profiles

Bgee: expression breadth broad, 89 present calls, max score 71.10.

Top tissues by expression

89 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	71.10	gold quality
lymph node	UBERON:0000029	65.77	gold quality
skeletal muscle tissue	UBERON:0001134	64.05	gold quality
islet of Langerhans	UBERON:0000006	62.54	gold quality
monocyte	CL:0000576	60.18	gold quality
prefrontal cortex	UBERON:0000451	58.86	gold quality
bone marrow	UBERON:0002371	58.64	gold quality
tonsil	UBERON:0002372	58.08	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	58.05	gold quality
muscle of leg	UBERON:0001383	56.62	gold quality
right lung	UBERON:0002167	56.51	gold quality
left adrenal gland cortex	UBERON:0035825	55.60	gold quality
blood	UBERON:0000178	55.33	gold quality
gastrocnemius	UBERON:0001388	55.07	gold quality
right lobe of liver	UBERON:0001114	54.30	gold quality
fallopian tube	UBERON:0003889	53.22	gold quality
right uterine tube	UBERON:0001302	52.99	gold quality
uterine cervix	UBERON:0000002	52.25	gold quality
endometrium	UBERON:0001295	51.24	gold quality
esophagus mucosa	UBERON:0002469	50.67	gold quality
heart left ventricle	UBERON:0002084	50.16	gold quality
esophagus	UBERON:0001043	50.03	gold quality
left adrenal gland	UBERON:0001234	49.55	gold quality
body of uterus	UBERON:0009853	49.47	gold quality
endocervix	UBERON:0000458	49.46	gold quality
amygdala	UBERON:0001876	49.13	gold quality
cerebellum	UBERON:0002037	48.90	silver quality
cerebellar hemisphere	UBERON:0002245	48.81	silver quality
frontal cortex	UBERON:0001870	48.67	gold quality
ascending aorta	UBERON:0001496	48.46	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.