TPBGL-AS1

Summary

TPBGL-AS1 (TPBGL antisense RNA 1, HGNC:55506) is a long non-coding RNA gene on chromosome 11q13.4.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:55506
Approved symbol	TPBGL-AS1
Name	TPBGL antisense RNA 1
Location	11q13.4
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000255136
Ensembl biotype	lncRNA
Entrez	105369388
RNAcentral	URS0000EECFD6 — lncRNA, 4556 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 7 — 7 lncRNA

ENST00000529491, ENST00000530792, ENST00000603012, ENST00000657165, ENST00000668494, ENST00000782719, ENST00000809844

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000529491 — 2 exons

Exon	Start	End
ENSE00002177403	75215209	75215485
ENSE00002195380	75210849	75211109

Expression profiles

Bgee: expression breadth ubiquitous, 110 present calls, max score 80.48.

Top tissues by expression

110 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
nucleus accumbens	UBERON:0001882	80.48	gold quality
putamen	UBERON:0001874	78.41	gold quality
superior frontal gyrus	UBERON:0002661	77.76	gold quality
caudate nucleus	UBERON:0001873	77.47	gold quality
right frontal lobe	UBERON:0002810	74.17	gold quality
frontal cortex	UBERON:0001870	74.00	gold quality
prefrontal cortex	UBERON:0000451	73.91	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.40	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	73.39	gold quality
cerebral cortex	UBERON:0000956	72.44	gold quality
anterior cingulate cortex	UBERON:0009835	71.94	gold quality
ventricular zone	UBERON:0003053	71.10	gold quality
primary visual cortex	UBERON:0002436	70.86	gold quality
amygdala	UBERON:0001876	69.86	gold quality
temporal lobe	UBERON:0001871	69.78	gold quality
brain	UBERON:0000955	68.92	gold quality
sural nerve	UBERON:0015488	68.85	gold quality
Ammon’s horn	UBERON:0001954	67.59	gold quality
hindlimb stylopod muscle	UBERON:0004252	66.43	gold quality
hypothalamus	UBERON:0001898	63.26	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.45	gold quality
cortical plate	UBERON:0005343	60.84	gold quality
ganglionic eminence	UBERON:0004023	57.77	silver quality
right hemisphere of cerebellum	UBERON:0014890	57.47	gold quality
cerebellar hemisphere	UBERON:0002245	57.11	gold quality
cerebellar cortex	UBERON:0002129	57.10	gold quality
cerebellum	UBERON:0002037	57.05	gold quality
islet of Langerhans	UBERON:0000006	56.44	gold quality
endocervix	UBERON:0000458	56.18	gold quality
urinary bladder	UBERON:0001255	55.69	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.