TPTE2-AS1

Summary

TPTE2-AS1 (TPTE2 antisense RNA 1, HGNC:42668) is a long non-coding RNA gene on chromosome 13q12.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:42668
Approved symbol	TPTE2-AS1
Name	TPTE2 antisense RNA 1
Location	13q12.11
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225316
Ensembl biotype	lncRNA
Entrez	100874136
RNAcentral	URS0002278345 — lncRNA, 1207 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000438640, ENST00000648281, ENST00000668715, ENST00000670337, ENST00000841739, ENST00000841740

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000438640 — 2 exons

Exon	Start	End
ENSE00001734535	19587968	19588350
ENSE00001793044	19587118	19587156

Expression profiles

Bgee: expression breadth ubiquitous, 119 present calls, max score 74.04.

Top tissues by expression

119 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	74.04	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.09	gold quality
cortical plate	UBERON:0005343	64.19	gold quality
ventricular zone	UBERON:0003053	61.00	gold quality
stromal cell of endometrium	CL:0002255	57.39	gold quality
endometrium	UBERON:0001295	57.33	gold quality
ganglionic eminence	UBERON:0004023	57.07	gold quality
lymph node	UBERON:0000029	56.21	gold quality
monocyte	CL:0000576	54.78	silver quality
placenta	UBERON:0001987	54.60	gold quality
tonsil	UBERON:0002372	54.43	gold quality
duodenum	UBERON:0002114	54.15	gold quality
vermiform appendix	UBERON:0001154	53.89	gold quality
gall bladder	UBERON:0002110	52.49	gold quality
bone marrow	UBERON:0002371	51.94	silver quality
blood	UBERON:0000178	51.73	silver quality
cortex of kidney	UBERON:0001225	51.55	gold quality
adrenal tissue	UBERON:0018303	50.43	silver quality
islet of Langerhans	UBERON:0000006	49.97	gold quality
liver	UBERON:0002107	49.69	silver quality
prefrontal cortex	UBERON:0000451	49.59	gold quality
descending thoracic aorta	UBERON:0002345	49.16	gold quality
smooth muscle tissue	UBERON:0001135	49.09	gold quality
calcaneal tendon	UBERON:0003701	49.04	silver quality
ovary	UBERON:0000992	48.90	gold quality
rectum	UBERON:0001052	48.82	gold quality
left ovary	UBERON:0002119	48.82	gold quality
urinary bladder	UBERON:0001255	48.53	gold quality
pancreas	UBERON:0001264	48.03	gold quality
primary visual cortex	UBERON:0002436	47.91	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.11

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.