TRAM2-AS1

Summary

TRAM2-AS1 (TRAM2 antisense RNA 1, HGNC:48663) is a long non-coding RNA gene on chromosome 6p12.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48663
Approved symbol	TRAM2-AS1
Name	TRAM2 antisense RNA 1
Location	6p12.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000225791
Ensembl biotype	lncRNA
Entrez	401264
RNAcentral	URS000075D190 — lncRNA, 2572 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 34 — 34 lncRNA

ENST00000453216, ENST00000605910, ENST00000606558, ENST00000606714, ENST00000653743, ENST00000653877, ENST00000657776, ENST00000658849, ENST00000662922, ENST00000663931, ENST00000664404, ENST00000664753, ENST00000666605, ENST00000666938, ENST00000667019, ENST00000667402, ENST00000847567, ENST00000847568, ENST00000847569, ENST00000847570, ENST00000847571, ENST00000847572, ENST00000847573, ENST00000847574, ENST00000847575, ENST00000847576, ENST00000847577, ENST00000847578, ENST00000847579, ENST00000847580, ENST00000847581, ENST00000847582, ENST00000847583, ENST00000847584

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453216 — 3 exons

Exon	Start	End
ENSE00003700010	52579375	52579609
ENSE00003855709	52596202	52596559
ENSE00003878827	52577588	52578594

Expression profiles

Bgee: expression breadth ubiquitous, 236 present calls, max score 90.75.

FANTOM5 (CAGE): breadth ubiquitous, TPM avg 1.3540 / max 19.5747, expressed in 975 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
68238	1.3540	975

Top tissues by expression

250 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	90.75	gold quality
kidney epithelium	UBERON:0004819	85.87	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.06	gold quality
pancreatic ductal cell	CL:0002079	84.25	gold quality
calcaneal tendon	UBERON:0003701	81.44	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.35	gold quality
cardiac muscle of right atrium	UBERON:0003379	80.59	silver quality
placenta	UBERON:0001987	80.16	gold quality
oviduct epithelium	UBERON:0004804	79.34	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	79.27	gold quality
epithelial cell of pancreas	CL:0000083	78.96	silver quality
islet of Langerhans	UBERON:0000006	78.94	gold quality
spinal cord	UBERON:0002240	78.48	gold quality
tendon	UBERON:0000043	78.37	gold quality
tibial artery	UBERON:0007610	78.19	gold quality
popliteal artery	UBERON:0002250	78.17	gold quality
pigmented layer of retina	UBERON:0001782	78.03	gold quality
corpus epididymis	UBERON:0004359	77.72	gold quality
substantia nigra	UBERON:0002038	77.50	gold quality
putamen	UBERON:0001874	77.14	gold quality
aorta	UBERON:0000947	77.06	gold quality
liver	UBERON:0002107	77.05	gold quality
right lobe of liver	UBERON:0001114	77.01	gold quality
right coronary artery	UBERON:0001625	77.00	gold quality
anterior cingulate cortex	UBERON:0009835	77.00	gold quality
hypothalamus	UBERON:0001898	76.90	gold quality
amygdala	UBERON:0001876	76.69	gold quality
tibialis anterior	UBERON:0001385	76.55	silver quality
medial globus pallidus	UBERON:0002477	76.52	gold quality
upper arm skin	UBERON:0004263	76.48	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.86

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.